Associate Director / Director, Total Rewards

Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been submitted to the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-3050, an IND-cleared FAP-targeted radiotherapy; and IM-1617, an IND-cleared solid tumor ADC. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview The Associate Director / Director, Total Rewards will strengthen engagement and retention by building a competitive, scalable, and employee-centered total rewards. This role will lead the design and administration of compensation practices, benefits, leave programs, 401(k), equity planning, and rewards & recognition ensuring our offerings attract, motivate, and retain top talent while remaining compliant, cost-effective, and aligned to our culture. Responsibilities Engagement and Retention Develop and execute a total rewards strategy that supports talent attraction, engagement, and retention. Partner with other functions of HR and business leaders to ensure rewards programs reinforce performance, internal equity, and our culture. Translate company growth and workforce needs into scalable and fiscally responsible rewards programs . Compensation Programs Lead the development, implementation, and ongoing management of compensation plans, including salary structures, incentive programs, market pricing, pay equity analysis, and compliance oversight. Support equity planning (new hire grants, promotions, refresh cycles, and annual planning) in coordination with Finance, Legal, and the equity administration partner. Prepare for and support the annual compensation cycle (merit, promotion, bonus planning as applicable): tools, timelines, manager guidance, calibration support, and reporting. Assist Chief Financial Officer by researching trends, gathering data and preparing compensation information to be reviewed by executive team, compensation committee, and board of directors. Benefits Administration Oversee day-to-day benefits administration including medical, dental, vision, life/AD&D, disability, FSA, and related programs. Own leave administration processes (e.g., FMLA, state leaves, disability coordination), ensuring an excellent employee experience and compliant practices. Manage 401(k) administration: vendor partnership, annual testing support, audits as needed, enrollment and education initiatives. Lead annual benefits renewal: plan design evaluation, cost modeling, vendor negotiations, open enrollment project management, and employee communications. Ensure compliance with applicable regulations (e.g., ERISA, COBRA, HIPAA, ACA) in partnership with legal/benefits vendors and internal stakeholders. Rewards & Recognition Own and improve recognition programs that reinforce values and performance (spot awards, peer recognition, and milestone/service awards). Partner with people leaders to ensure recognition is timely , inclusive, and consistently applied across teams. Stakeholder Partnership & Influence Serve as a strategic advisor to leaders on total rewards decisions, tradeoffs, and communications. Collaborate closely with HRBPs, Talent Acquisition team, Payroll, Finance, Legal, and People Operations to ensure seamless program delivery. Lead vendor relationships (brokers, carriers, leave administrator, 401(k) provider, compensation survey partners, recognition platform). Measurement & Continuous Improvement Monitor costs, utilization , participation, and employee feedback to refine offerings and improve experience. Create scalable documentation, SOPs, and governance for all total rewards programs. Qualifications Bachelor’s Degree required . A minimum of 8+ years of progressive experience in Total Rewards, Compensation, Benefits, or HR, including program ownership in a scaling organization. Biotech/life science industry experience is strongly preferred. Knowledge and Skills Hands-on experience with benefits administration (health plans, leave administration, 401(k)) and vendor management. Strong compensation experience including benchmarking roles, creating job architecture/leveling frameworks administering annual compensation cycles, and supporting sales incentive programs . Demonstrated experience with equity administration platforms and stock plan basics. Strong analytical skills (modeling, reporting, and presenting insights) and ability to translate data into clear recommendations . Strong stakeholder influence and experience partnering cross-functionally with Finance, Legal, Payroll, and senior leaders. Excellent facilitation, program design, and communication skills. Washington State Pay Range $175,048 — $247,592 USD E/E/O Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. E-Verify Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish) .

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