Project Manager (CMC / Development Operations)

Who Are We? Our company is based on the science of our founder, Stanley Qi, one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. Instead, we regulate the epigenome to suppress and activate multiple genes simultaneously. We are further evolving the platform and leveraging its strengths to address unmet medical needs. We are looking for exceptional team members who want an active role in building a rapidly growing biotech. Position: Project Manager (CMC / Development Operations) Location: South San Francisco, CA Remote, Hybrid and In Person options Opportunity : Epicrispr Biotechnologies is seeking a highly organized and proactive Project Manager to support execution of CMC and cross-functional development programs. This role will initially focus heavily on CMC project management, including oversight of manufacturing activities at CMOs, and will expand over time to support broader product development initiatives across the organization. Roles and Responsibilities : Oversee execution of manufacturing runs at Contract Manufacturing Organizations (CMOs) for lead programs, including tracking completion of action items, monitoring program activities and milestones, and driving resolution of risks and issues across the cross-functional team Serve as key alliance manager for CMC vendors in partnership with the VP of Tech Ops, ensuring effective collaboration and execution across external partners Track and maintain visibility of program timelines, dependencies, and deliverables across CMC and broader development workstreams using appropriate tracking tools Organize, schedule, and facilitate internal cross-functional program meetings to ensure alignment and clear communication across teams Maintain, organize, and continuously improve program documentation, trackers, and repositories (e.g., Smartsheet, SharePoint) Document key decisions, risks, assumptions, issues, action items, and overall program plans in a clear and structured manner Provide clear, timely communication of program status updates, risks, and key decisions to leadership and relevant stakeholders Coordinate across CMC, Clinical, Regulatory, and Nonclinical teams to ensure alignment and execution of integrated program deliverables Support planning and coordination of key nonclinical and regulatory milestones as needed to enable program execution Partner with the Associate Director to identify, develop, and implement opportunities to streamline and standardize project management processes, tools, and workflows across Epicrispr Help build scalable project management infrastructure that improves visibility, accountability, and execution discipline across programs and teams Requirements : Bachelor’s degree required; Master’s degree preferred 3–7+ years of experience in project or program management within biotechnology, pharmaceutical, or life sciences environments Strong experience in CMC, manufacturing, or technical operations preferred Proficiency with project tracking tools such as Smartsheet and SharePoint Strong organizational, communication, and documentation skills Ability to manage multiple priorities in a fast-paced, dynamic environment Strong attention to detail and commitment to follow-through and accountability Comfortable working in ambiguous, early-stage biotech environments Strong interpersonal skills with the ability to collaborate across technical and non-technical teams Ability to manage conflict and remain composed under pressure Experience in startup or rapidly scaling biotech environments is a plus Compensation: The salary range for this position is $140,000 to $150,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location. Epicrispr Biotechnologies is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation. Our proprietary platform represents an entirely new class of therapeutics that can be leveraged to treat severe disease across numerous therapeutic areas, including complex diseases impacted by multiple genes. Epicrispr Biotechnologies provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

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