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Director of Clinical Data Management

Pathos · New York City, NY, United States · On Site · Deleted · $215,000–$240,000 / year · Rippling ATS

Job facts

FieldValue
CompanyPathos
TitleDirector of Clinical Data Management
Normalized title-
Department / teamClinical
LocationNew York City, NY, United States
Work modelOn Site
Employment typeFull Time
Salary$215,000–$240,000 / year
Statusdeleted
ATS providerRippling ATS
Posted / first seen2026-05-21 / 2026-05-29
Changed / last seen2026-06-14 / 2026-06-12

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City jobsActive postings in New York City.Open
Department jobsActive postings in Clinical.Open
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Linked records

CompanyPathos
Source2d66e9b5-1b63-475c-a03a-943980720722
ATS providerRippling ATS

Description

company Drug development shouldn’t be guesswork, not when patients are waiting. Pathos is building a next-generation biotech with AI at the core. Not as a feature, but as the operating system for how medicines get developed. We believe most drugs don't fail because the science was wrong. They fail because they were tested in the wrong patients, with the wrong assumptions, in trials that couldn't answer the real question: who benefits, and why? Pathos exists to change that. We're building the largest foundation model in oncology and pairing it with proprietary AI systems, deep oncology expertise, and 200+ petabytes of multimodal data linked to patient outcomes, so we can make development decisions with more precision, much earlier. This is not theoretical. We’re well-capitalized and have the leadership to build a generational company. We invest in and advance our own clinical-stage programs, using our AI platform to sharpen trial design, patient selection and biomarker strategy. So therapies reach the patients most likely to benefit, sooner. How We Build Pathos does not operate like a traditional biotech. There is no middle management. There are no layers of approval. The company is designed, from the ground up, around small teams of 2–4 subject matter experts who each command hundreds of AI agents to do the work that used to require dozens of people. Everyone builds. Everyone ships. Every function at Pathos — from clinical execution to asset selection to the foundation model itself — runs on this model. Our product velocity delivers meaningful outcomes in hours instead of weeks. This is not a future aspiration. It is how we operate today. The people who thrive here are operators: deep experts who can specify what needs to happen, orchestrate AI agents to execute at scale, and make high-judgment calls that compound over time. If you have spent your career building and shipping AI systems at scale, this is the environment where that experience becomes a superpower. role About the Role The Director of Clinical Data Management will establish and lead the clinical data management function at Pathos. You will own clinical data collection, cleaning, and integrity across our oncology trials, ensuring our datasets are ready for analysis, regulatory submissions, and the next development decision. You will report to the Vice President, Head of Clinical Operations. This is the first CDM hire at Pathos. There is no existing playbook. You will write it. You will define how Pathos collects, cleans, and locks clinical data in a company built on small teams and AI agents, and you will set the standard for what audit ready trial data looks like in this operating model. The role sits at the intersection of clinical data discipline and an AI native operating model. You will spend less time chasing CRO status reports and more time on the data questions that move trials forward, because AI agents will absorb the routine query resolution, status tracking, discrepancy review, and document compilation work that traditionally consumed a CDM Director's calendar. What You Will Do Own clinical data strategy and oversight Lead oversight of data management for outsourced clinical trials, including project planning, vendor coordination, internal review cycles, data cleaning, and approval of deliverables. Oversee CRO and vendor activities to ensure GCP compliance and execution against protocols and SOPs. Own consistency across trials and programs: CRF design and standards, Data Management Plans, CRF annotation and completion guidelines, edit check specifications, data entry and query status tracking, and database lock. Drive timely database lock, data quality, and readiness for statistical analysis and regulatory submissions. Direct AI agents to draft DMPs, edit check specs, and reconciliation reports, and apply your judgment to the final product. Execute vendor and CRO management Manage CROs and vendors delivering CDM services, holding them to timelines, budgets, and quality standards. Develop and monitor Data Management Plans, Data Review Plans, and data transfer specifications. Resolve complex data issues, queries, and discrepancies in partnership with clinical and statistical teams. Use AI agents to compare vendor deliverables against specifications, surface drift early, and prepare structured feedback for vendor reviews. Build cross functional partnerships Serve as the primary CDM partner on every study team. Partner with Biostatistics, Clinical Operations, Medical Monitoring, and Data Science colleagues so that data supports trial endpoints and regulatory deliverables. Collaborate on the integration of clinical trial data with Pathos AI platforms and real world data sources so that operational data feeds back into model performance and decision support. Lead, scale, and stay compliant Build and scale the CDM function as the company grows, including hiring and mentoring future staff. Develop SOPs, best practices, and quality frameworks that meet GCP, ICH, CDISC, and 21 CFR Part 11 expectations. Contribute to portfolio level planning and operational strategy, and translate CDM signals into actionable input for Clinical Operations leadership. Who You Are Minimum Qualifications Bachelor's or Master's degree in Life Sciences, Data Management, or a related field. 10 or more years of progressive experience in clinical data management, including leadership of oncology trials. Deep working knowledge of EDC systems such as Medidata Rave, Veeva CDMS, or Oracle InForm, and clinical data standards including CDISC, SDTM, and ADaM. Demonstrated ability to manage CROs and vendors against quality, timeline, and budget commitments. Strong command of GCP, ICH, FDA, CDISC, GCDMP, 21 CFR Part 11, MedDRA, and WHO Drug Dictionaries, and how they apply in daily CDM practice. Strongly Preferred Experience operating in a flat, builder oriented organization where you specify, orchestrate, and ship rather than manage process. Experience gathering requirements and writing specifications for database integrations, including ePRO, central and local laboratory data uploads, supply management, IVRS, and IWRS. Experience building a CDM function from the ground up or substantially rebuilding one in a small company environment. Comfort orchestrating AI tools or agentic workflows in clinical data work, and clear instinct for where automation belongs and where human review must stay. Location This position is based at our New York City HQ, though exceptional remote candidates may also be considered.

Full job record

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Source ID2d66e9b5-1b63-475c-a03a-943980720722
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Providerrippling
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TitleDirector of Clinical Data Management
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Statusdeleted
Activeno
Location TextNew York City, NY, United States
DepartmentClinical
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Employment Typefull_time
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CountryUnited States
RegionNY
CityNew York City
Salary RawUSD 215000-240000 YEAR
Salary Min215,000
Salary Max240,000
Salary CurrencyUSD
Salary Periodyear
Source URLhttps://ats.rippling.com/pathos/jobs/b3f8f5f8-4f53-46b0-b9e2-1d329b4ba986
Apply URLhttps://ats.rippling.com/pathos/jobs/b3f8f5f8-4f53-46b0-b9e2-1d329b4ba986
First Seen At2026-05-29 07:13:53Z
Last Seen At2026-06-12 09:57:07Z
Last Checked At2026-06-14 08:46:34Z
Last Changed At2026-06-14 08:46:34Z
Inactive At2026-06-14 08:46:34Z
Source Posted At2026-05-21 20:42:33Z
Source Updated At—
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      "role": "<meta><h2 style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;line-height:1.6;font-size:29pt;font-weight:600;letter-spacing:0.5px;margin-top:18px;margin-bottom:4px;padding-left:0px;\"><span style=\"color:rgb(0,0,0);font-size:14pt;white-space:pre-wrap;\">About the Role</span></h2><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">The Director of Clinical Data Management will establish and lead the clinical data management function at Pathos. You will own clinical data collection, cleaning, and integrity across our oncology trials, ensuring our datasets are ready for analysis, regulatory submissions, and the next development decision. You will report to the Vice President, Head of Clinical Operations.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">This is the first CDM hire at Pathos. There is no existing playbook. You will write it. You will define how Pathos collects, cleans, and locks clinical data in a company built on small teams and AI agents, and you will set the standard for what audit ready trial data looks like in this operating model.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">The role sits at the intersection of clinical data discipline and an AI native operating model. You will spend less time chasing CRO status reports and more time on the data questions that move trials forward, because AI agents will absorb the routine query resolution, status tracking, discrepancy review, and document compilation work that traditionally consumed a CDM Director's calendar.</span></p><h2 style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;line-height:1.6;font-size:14pt;font-weight:600;letter-spacing:0.5px;margin-top:18px;margin-bottom:4px;padding-left:0px;\"><span style=\"color:rgb(0,0,0);font-size:14pt;white-space:pre-wrap;\">What You Will Do</span></h2><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Own clinical data strategy and oversight</strong></b></p><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Lead oversight of data management for outsourced clinical trials, including project planning, vendor coordination, internal review cycles, data cleaning, and approval of deliverables.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Oversee CRO and vendor activities to ensure GCP compliance and execution against protocols and SOPs.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Own consistency across trials and programs: CRF design and standards, Data Management Plans, CRF annotation and completion guidelines, edit check specifications, data entry and query status tracking, and database lock.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Drive timely database lock, data quality, and readiness for statistical analysis and regulatory submissions.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Direct AI agents to draft DMPs, edit check specs, and reconciliation reports, and apply your judgment to the final product.</span></li></ul><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Execute vendor and CRO management</strong></b></p><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Manage CROs and vendors delivering CDM services, holding them to timelines, budgets, and quality standards.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Develop and monitor Data Management Plans, Data Review Plans, and data transfer specifications.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Resolve complex data issues, queries, and discrepancies in partnership with clinical and statistical teams.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Use AI agents to compare vendor deliverables against specifications, surface drift early, and prepare structured feedback for vendor reviews.</span></li></ul><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Build cross functional partnerships</strong></b></p><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Serve as the primary CDM partner on every study team.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Partner with Biostatistics, Clinical Operations, Medical Monitoring, and Data Science colleagues so that data supports trial endpoints and regulatory deliverables.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Collaborate on the integration of clinical trial data with Pathos AI platforms and real world data sources so that operational data feeds back into model performance and decision support.</span></li></ul><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Lead, scale, and stay compliant</strong></b></p><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Build and scale the CDM function as the company grows, including hiring and mentoring future staff.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Develop SOPs, best practices, and quality frameworks that meet GCP, ICH, CDISC, and 21 CFR Part 11 expectations.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Contribute to portfolio level planning and operational strategy, and translate CDM signals into actionable input for Clinical Operations leadership.</span></li></ul><h2 style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;line-height:1.6;font-size:14pt;font-weight:600;letter-spacing:0.5px;margin-top:18px;margin-bottom:4px;padding-left:0px;\"><span style=\"color:rgb(0,0,0);font-size:14pt;white-space:pre-wrap;\">Who You Are</span></h2><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Minimum Qualifications</strong></b></p><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Bachelor's or Master's degree in Life Sciences, Data Management, or a related field.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">10 or more years of progressive experience in clinical data management, including leadership of oncology trials.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Deep working knowledge of EDC systems such as Medidata Rave, Veeva CDMS, or Oracle InForm, and clinical data standards including CDISC, SDTM, and ADaM.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Demonstrated ability to manage CROs and vendors against quality, timeline, and budget commitments.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Strong command of GCP, ICH, FDA, CDISC, GCDMP, 21 CFR Part 11, MedDRA, and WHO Drug Dictionaries, and how they apply in daily CDM practice.</span></li></ul><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Strongly Preferred</strong></b></p><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Experience operating in a flat, builder oriented organization where you specify, orchestrate, and ship rather than manage process.</span></li></ul><ul data-pattern=\"discCircleSquare\" data-depth=\"1\" style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;\"><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Experience gathering requirements and writing specifications for database integrations, including ePRO, central and local laboratory data uploads, supply management, IVRS, and IWRS.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Experience building a CDM function from the ground up or substantially rebuilding one in a small company environment.</span></li><li style=\"color:rgb(0,0,0);font-size:12pt;--listitem-marker-color:#000000;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Comfort orchestrating AI tools or agentic workflows in clinical data work, and clear instinct for where automation belongs and where human review must stay.</span></li></ul><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:14pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:14pt;white-space:pre-wrap;\">Location</strong></b></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">This position is based at our New York City HQ, though exceptional remote candidates may also be considered.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p>",
      "company": "<meta><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Drug development shouldn’t be guesswork, not when patients are waiting.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Pathos is building a next-generation biotech with AI at the core. Not as a feature, but as the operating system for how medicines get developed. We believe most drugs don't fail because the science was wrong. They fail because they were tested in the wrong patients, with the wrong assumptions, in trials that couldn't answer the real question: who benefits, and why?</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Pathos exists to change that. We're building the largest foundation model in oncology and pairing it with proprietary AI systems, deep oncology expertise, and 200+ petabytes of multimodal data linked to patient outcomes, so we can make development decisions with more precision, much earlier.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"font-size:12pt;white-space:pre-wrap;\">This is not theoretical. We’re well-capitalized and have the leadership to build a generational company. We invest in and advance our own clinical-stage programs, using our AI platform to sharpen trial design, patient selection and biomarker strategy. So therapies reach the patients most likely to benefit, sooner.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><b><strong style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">How We Build</strong></b></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Pathos does not operate like a traditional biotech. There is no middle management. There are no layers of approval. The company is designed, from the ground up, around small teams of </span><span style=\"font-size:12pt;white-space:pre-wrap;\">2–4</span><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\"> subject matter experts who each command hundreds of AI agents to do the work that used to require dozens of people.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"color:rgb(0,0,0);font-size:12pt;white-space:pre-wrap;\">Everyone builds. Everyone ships. Every function at Pathos — from clinical execution to asset selection to the foundation model itself — runs on this model. Our product velocity delivers meaningful outcomes in hours instead of weeks. This is not a future aspiration. It is how we operate today.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><span style=\"font-size:12pt;white-space:pre-wrap;\">The people who thrive here are operators: deep experts who can specify what needs to happen, orchestrate AI agents to execute at scale, and make high-judgment calls that compound over time. If you have spent your career building and shipping AI systems at scale, this is the environment where that experience becomes a superpower.</span></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p><p style=\"font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:12pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;\"><br></p>"
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