Senior Director, US Marketing Operations

Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/ , and follow us on X , LinkedIn and Facebook . Role Summary : The Senior Director, Marketing Operations leads and actively operates Dyne’s marketing operations function, combining enterprise ‑ level leadership with hands ‑ on ownership of critical capabilities. This role is accountable for designing, scaling, and governing marketing operations, while remaining closely engaged in execution, decision ‑ making, and problem ‑ solving across high ‑ impact workstreams. The Senior Director partners closely with Marketing, Field, Medical, Legal, Regulatory, Compliance, IT, and Commercial Operations to ensure promotional review, customer engagement programs, congresses, meetings, omnichannel enablement, and external funding activities are executed with speed, quality, and compliance. This role directly drives operational outcomes, removes friction, makes portfolio tradeoffs, and builds scalable operating models for future growth. This role is based in Waltham, MA. Primary Responsibilities Include: Enterprise Strategy, Operating Model, and Performance Sets direction and owns the enterprise marketing operations operating model across brands and therapeutic areas Partners with Finance, Procurement, and IT on resourcing, tools, and integrated planning Builds and governs a multi ‑ year capability roadmap to support launches and portfolio growth Drives prioritization, metrics, and performance management across Marketing Operations Advises senior leadership on operational performance, risk, and tradeoffs Promotional Review and External Engagement Governance Sets and scales the PRC/MLR operating model, including governance, capacity planning, vendor strategy, and SOPs Owns enterprise KPIs and continuous improvement initiatives Is accountable for sustained on ‑ time performance, quality, surge readiness, and cross ‑ brand prioritization Sets enterprise governance for sponsorships and grants, ensuring consistent controls, portfolio visibility, and audit ‑ ready processes Customer Engagement Programs: Peer ‑ to ‑ Peer, Congresses, Meetings, and KOLs Owns portfolio ‑ level governance for peer ‑ to ‑ peer education, including operating standards, compliance guardrails, and vendor oversight Partners with Field leadership on execution cadence, capacity planning, and investment alignment Oversees portfolio congress strategy and multi ‑ brand operational integration Sets the enterprise approach for KOL engagement operations, including governance, vendor strategy, and policy alignment Owns enterprise meeting strategy (e.g., NSMs, POAs), including calendar governance, capacity planning, and cost and quality standards Print, Fulfillment, and Omnichannel Enablement Owns enterprise print and fulfillment strategy, including vendor governance, risk mitigation, and cost ‑ to ‑ serve optimization Sets omnichannel and field enablement standards across brands, including deployment, taxonomy, measurement, and system integration Establishes KPIs for content deployment, adoption, and content health Guides cross ‑ functional execution across Marketing, Medical, Legal, Regulatory, Compliance, IT, and Commercial Operations Education and Skills Requirements: Bachelor’s degree in a relevant discipline required; Master’s degree preferred 15+ years of progressive experience in pharmaceutical or biotechnology marketing operations, commercial operations, or related functions, or equivalent experience Demonstrated experience leading enterprise ‑ or portfolio ‑ level operating models in highly regulated environments Extensive experience with promotional compliance, governance, and risk management across multiple brands or therapeutic areas Proven experience leading, coaching, and developing senior ‑ level leaders and managers Strategic, enterprise ‑ level leader with the ability to define vision, set standards, and govern execution at scale Strong judgment in navigating complex, ambiguous operational challenges while balancing speed, quality, and compliance Ability to influence senior leaders and executives through clear recommendations, data ‑ driven insights, and thoughtful tradeoffs Deep expertise in portfolio prioritization, capacity planning, and resource allocation Strong understanding of cross ‑ functional interdependencies and integrated commercial systems Inclusive, values ‑ driven leader who models accountability, collaboration, and continuous improvement #LI-Onsite MA Pay Range $224,000 — $290,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

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