Bioinformatics Pipeline Validation Manager with Cancer genomics exp (Remote -US)

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    "description": "<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; text-decoration: underline\"><span style=\"font-weight: bold\">Bioinformatics Pipeline Validation Manager with Cancer genomics exp (Remote -US)</span></span><br><br><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">We are looking to hire a candidate with the skills sets mentioned and experience for one of our clients within the life science Industry.  </span><br></p>\n<p><br><span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><span style=\"font-weight: bold\">Location:</span> Flexible (Remote) – Must overlap <span style=\"font-weight: bold\">at least 5 hours with EST</span> daily</span><br><br></p>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Job summary<br></span></p>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">We are seeking an experienced Bioinformatics Pipeline Validation Manager to lead validation efforts for bioinformatics pipelines. This individual will manage a team responsible for ensuring that computational pipelines used in genomics and clinical research meet regulatory, quality, and performance standards. This role is within a <span style=\"font-weight: bold\">life sciences organization</span> focused on advancing molecular diagnostics and genomic technologies.</span><br><br></p>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">The ideal candidate will bring strong <span style=\"font-weight: bold\">bioinformatics, NGS pipeline validation, Cancer genomics and clinical diagnosis experience and leadership experience</span>, along with a deep understanding of regulated environments such as <span style=\"font-weight: bold\">GxP, CLIA, or CAP</span>.</span><br><br></p>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><span style=\"font-weight: bold\">Key Responsibilities<br><br></span></span></p>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Leadership &amp; Team Management</span></p>\n<ul>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Lead, mentor, and develop a team of bioinformatics validation scientists and analysts.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Oversee workload planning, project assignments, and team performance tracking.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Foster a collaborative, high-performing team culture focused on quality, efficiency, and innovation.</span></li>\n</ul>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Pipeline Validation &amp; Quality Assurance</span></p>\n<ul>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Own end-to-end validation of bioinformatics pipelines, including NGS, WGS/WES, RNA-seq, variant calling, annotation, and QC workflows.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Develop and execute validation plans, protocols, test cases, and acceptance criteria.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Ensure pipelines meet applicable regulatory requirements (e.g., CLIA, CAP, FDA).</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Perform software verification and validation (SV&amp;V) and document results thoroughly.</span></li>\n</ul>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Technical Expertise &amp; Execution</span></p>\n<ul>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Collaborate with bioinformatics engineers, data scientists, and software developers to optimize pipeline design and performance.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Evaluate new tools, algorithms, and software for integration into analytical workflows.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Troubleshoot pipeline issues and lead root-cause analysis efforts.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Ensure reproducibility, scalability, and robustness of computational workflows.</span></li>\n</ul>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Cross-Functional Collaboration</span></p>\n<ul>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Partner with wet lab teams, QA, clinical operations, and product management to align validation objectives with timelines and business goals.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Represent the validation team in client meetings, audits, and technical reviews.</span></li>\n</ul>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Documentation &amp; Compliance</span></p>\n<ul>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Maintain detailed documentation of validation activities, including version control and release notes.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Prepare documentation for regulatory submissions and internal audits.</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\">Establish and enforce validation standards, SOPs, and best practices.</span><br><br></li>\n</ul>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><span style=\"font-weight: bold\"><br></span></span></p>\n<p><span style=\"font-weight: bold\">Required Qualifications</span></p>\n<ul>\n<li>10+ years of experience in bioinformatics, genomics data analysis, cancer genomics and clinical diagnosis exp pipeline validation.</li>\n<li>4+ years of leadership or management experience leading technical teams.</li>\n<li>Strong experience with NGS data processing pipelines, including quality control, alignment, variant calling, annotation, and interpretation.</li>\n<li>Hands-on experience with bioinformatics workflow management tools such as Nextflow, Snakemake, WDL, Cromwell, or Galaxy.</li>\n<li>Experience with common NGS analysis tools such as BWA, Bowtie2, GATK, SAMtools, Picard, FastQC, MultiQC, and VEP/ANNOVAR.</li>\n<li>Experience with containerization and reproducibility tools such as Docker, Singularity/Apptainer, and workflow environment management tools like Conda or Bioconda to ensure reproducible bioinformatics pipelines.</li>\n<li>Proficiency in scripting or programming languages such as Python, R, or Bash.</li>\n<li>Experience working in regulated environments (GxP, CLIA, CAP, or similar).</li>\n<li>Familiarity with software validation lifecycle, automated testing, and documentation practices.</li>\n<li>Bachelor’s or master’s degree in bioinformatics, Computational Biology, Genomics, Computer Science, or related field.<br><br></li>\n</ul>\n<p><span style=\"font-weight: bold\">Preferred Qualifications</span></p>\n<ul>\n<li>Experience supporting clinical genomics or diagnostic pipelines.</li>\n<li>Knowledge of cloud platforms such as AWS, Google Cloud Platform, or Azure used for scalable bioinformatics workflows.</li>\n<li>Experience with CI/CD tools such as Jenkins, GitLab CI, or GitHub Actions.</li>\n<li>Experience managing large-scale genomic datasets and distributed computing environments.</li>\n</ul>\n<p> <span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><br></span></p>\n<p><span style=\"font-family: Inter, sans-serif; font-size: 12pt; font-weight: bold\">Other Job Details:<br><br></span></p>\n<ul>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><span style=\"font-weight: bold\">Location: </span>Remote</span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><span style=\"font-weight: bold\">Candidate rate: : <span style=\"text-decoration: underline\">$65 on C2C and $60 on W2</span></span></span></li>\n<li><span style=\"font-family: Inter, sans-serif; font-size: 12pt\"><span style=\"font-weight: bold\">Docs required:</span> ID proof will be required.</span></li>\n</ul>",
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