Director, Global Strategy Lead

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Director, Global Strategy Lead as part of the Strategy and CI team based in Bridgewater, NJ . Role Overview The Director, Global Strategy Lead will lead enterprise transformation initiatives across the organization, integrating Strategy, and Lean methodologies to drive sustainable business impact. This role will establish and deploy a structured approach to portfolio management, continuous improvement, and strategic execution aligned with company priorities. This leader will be responsible for designing and implementing transformation frameworks that enhance visibility, accountability, and delivery across a global portfolio of initiatives. Projects will include strategic initiatives, operational excellence programs, KPI/dashboard development, organizational redesign, and end-to-end process improvements. Additionally, this role will champion a culture of continuous improvement, leveraging Lean principles and best practices inspired by systems such as the Danaher Business System (DBS), while coaching cross-functional leaders and project teams to deliver measurable results aligned with the company’s mission and long-term strategy. Key Responsibilities Establish and lead the enterprise strategic planning, and Lean continuous improvement. Develop and execute a standardized framework to manage transformation initiatives and ensure alignment with business strategy and priorities. Own and actively manage the enterprise portfolio of strategic and operational initiatives, ensuring prioritization, resource alignment, and execution discipline. Partner with executive leadership to translate strategy into actionable roadmaps, with clear milestones, KPIs, and accountability. Translate commercial strategy into executable initiatives with clear KPIs, timelines, and accountability. Partner with CI team to ensure seamless flow of information with Bus on Strategic imperatives Partner with Sales, Marketing, Market Access, and Customer Experience teams to drive execution excellence. Drive implementation of Lean methodologies and continuous improvement practices across functions to improve efficiency, quality, and performance. Build and maintain executive-level dashboards and reporting mechanisms to provide visibility into transformation progress, risks, and outcomes. Lead regular portfolio reviews with senior leadership to assess progress, reprioritize initiatives, and ensure alignment with evolving business needs. Facilitate cross-functional collaboration to remove barriers, accelerate decision-making, and ensure successful delivery of key initiatives. Champion a culture of accountability, performance management, and continuous improvement throughout the organization. Ensure sustainability of transformation outcomes through standardization, capability building, and change management. This role requires individual to make decisions promptly and seeking alignment with GM in China as processes move to implementation. Approvals related to budget and strategic shifts for commercial/pipeline will require higher-level approvals. Requirements Bachelor’s Degree in science required; MBA or advanced degree preferred. Background in Pharma/Biotech is essential. 10+ years of experience in transformation, strategy, or operational excellence roles. Proven experience leading enterprise-wide transformation initiatives in complex, matrixed organizations. Strong background in strategic execution required Demonstrated expertise in Lean methodologies (e.g., Kaizen, Value Stream Mapping, Daily Management). Experience with Danaher Business System (DBS) or similar performance/Lean systems strongly preferred. Exceptional leadership, facilitation, and influencing skills across all levels of the organization. Strong analytical and problem-solving capabilities with a data-driven mindset. Excellent communication and executive presentation skills. Ability to manage multiple priorities and drive results in a fast-paced, dynamic environment. Strong change management and organizational development experience. #Li-LB1 #Li-Hybrid The base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws. Other Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles. Benefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work. Pay Range (Base Pay): $193,629 — $254,137 USD Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice .

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