VP, Global Manufacturing and Supply Chain

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    "location": {
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      "state": "California",
      "postalCode": "94080",
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    "datePosted": "2026-06-24",
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    "description": "<p>Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.</p>\n<p><br></p>\n<p>Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February of 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.</p>\n<p><br></p>\n<p><span style=\"text-decoration: underline\"><span style=\"font-weight: bold\">POSITION SUMMARY</span></span><br>As we continue to advance our innovative product pipeline and progress our lead obesity development program towards commercialization and launch, we are seeking a Vice President, Global Manufacturing &amp; Supply Chain reporting to the SVP of Technical Operations to lead our end-to-end manufacturing, supply chain and commercial readiness activities.  As a strategic and results-oriented senior leader within Technical Operations, this individual will be responsible for building a high performing manufacturing and supply chain function and establishing the necessary organization, business processes and systems required to ensure reliable and efficient product global supply and commercial launch readiness. This role requires deep expertise in small molecule pharmaceutical operations, an understanding of the pharmaceutical product development lifecycle, excellent business acumen and the ability to thrive in a dynamic, fast-paced environment. Excellent communication skills are a must for this multidisciplinary and global effort.</p>\n<p><br></p>\n<p><span style=\"text-decoration: underline\"><span style=\"font-weight: bold\">KEY RESPONSIBILITIES</span></span><br>External Manufacturing</p>\n<ul>\n<li>Develop and lead the external manufacturing strategy across DS, DP, and packaged/finished product to support global clinical trials and commercial supply.</li>\n<li>Establish external manufacturing team, process, governance, KPIs, working agreements and business review cadence with partnership mindset and monitor execution and ongoing production performance.</li>\n<li>Ensure reliable execution of manufacturing operations to meet PDUFA, launch, and ongoing supply needs—including campaign planning, batch release, and issue resolution.</li>\n<li>Lead CDMO governance and relationship management, including executive-level interactions, KPIs, and escalation pathways.</li>\n<li>Serve as the executive leader and primary point of accountability for CDMO performance, including quality, timelines, cost, and compliance.</li>\n<li>Partner with Quality and Regulatory to ensure GMP compliance, inspection readiness, and alignment with global regulatory expectations.</li>\n<li>Collaborate cross-functionally with CMC Development, Quality, Supply Chain, and Regulatory to align on technical transfers, validation strategies, and lifecycle management.</li>\n<li>Proactively identify risks and implement mitigation plans to ensure continuity and robustness of external manufacturing operations.</li>\n<li>Provide strategic input into make/buy decisions, site selection, and future-state network design.</li>\n<li>Support business development and sourcing efforts related to manufacturing.  Lead CDMO strategic sourcing and selection efforts from needs definition to RFP to selection and start-up to secure the necessary CDMO capabilities and capacities to meet all product supply needs.</li>\n</ul>\n<p><br></p>\n<p>Global Supply Chain and Commercial Readiness</p>\n<ul>\n<li>Oversee supply of clinical trial materials across global studies in alignment with Clinical Operations, CMC, and Regulatory teams.</li>\n<li>Direct global demand forecasting, supply planning, and inventory strategies to support clinical and commercial needs.</li>\n<li>Serve as a key Technical Operations leader contributing to company level global launch strategies and tactical plans.  </li>\n<li>Lead commercial launch execution activities within Tech Ops.</li>\n<li>Ensure adequate capacity planning, tech transfer, and commercial-scale readiness in coordination with Technical Operations and Quality.</li>\n<li>Select and implement the necessary planning and performance/risk monitoring tools to enhance visibility and data availability within the supply chain.</li>\n<li>Oversee global logistics and distribution, 3PL selection and oversight, serialization and anticounterfeiting programs and ensure compliance with all global trade regulations.</li>\n<li>Carry out an interim global PM role as Structure grows &amp; help develop timelines and key activities.  </li>\n</ul>\n<p><span style=\"text-decoration: underline\"><br></span></p>\n<p><span style=\"text-decoration: underline\"><span style=\"font-weight: bold\">QUALIFICATIONS</span></span></p>\n<ul>\n<li>Minimum bachelor’s degree in supply chain, Engineering, or related field (MBA preferred).</li>\n<li>20+ years of progressive leadership experience in biopharmaceutical manufacturing, supply chain, technical operations with at least 5+ years’ experience in external CDMO management.</li>\n<li>Proven success in building or scaling manufacturing and supply chain teams and leading new product launches.</li>\n<li>Deep understanding of GMP compliance, Regulatory CMC expectations and global supply chain requirements.</li>\n<li>Experience with small molecule API manufacturing, oral solid dosage forms and combination products.</li>\n<li>Deep understanding of GMP, GDP, and international regulatory requirements, with launch readiness experience in the U.S. and EU markets.</li>\n<li>Excellent business acumen and demonstrated ability to think strategically and ensure excellence in execution in complex programs operation under tight timelines and budgets.</li>\n<li>Excellent leadership, communication, and cross-functional collaboration skills.  Ability to influence internal and external stakeholders.</li>\n<li>Partnership mindset and ability to build relationships with key partners in Quality, Regulatory, CMC, Technical Operations, R&amp;D and Commercial functions.</li>\n<li>Demonstrated success in building scalable teams, leading complex projects and driving accountability in matrixed organizations</li>\n</ul>\n<p><br></p>\n<p><span style=\"font-weight: bold\">Travel Required:</span><span> Up to 30%</span></p>\n<p><br></p>\n<p><span style=\"font-weight: bold\">Structure Therapeutics Inc. is an Equal-Opportunity Employer.</span></p>\n<p>Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is <span>$300,000 - $390,000</span> The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.</p>\n<p><br></p>\n<p>At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.</p>\n<p><br><br></p>\n<p><span style=\"font-weight: bold\">Notice to Recruiters/Staffing Agencies</span></p>\n<p>Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees.</p>\n<p><br></p>\n<p>We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.</p>\n<p><br></p>\n<p>Structure Therapeutics’ receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees.</p>\n<p><br><br></p>\n<p><span style=\"font-weight: bold\">Fraud Alert</span></p>\n<p>To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at <a href=\"https://structuretx.bamboohr.com/careers\" target=\"_blank\" rel=\"noopener noreferrer\">BambooHR</a>.</p>\n<p><br></p>\n<p>Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.</p>",
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