Staff Cloud Infrastructure, Scientific Computer Engineer

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking a Staff Cloud Infrastructure, Scientific Computer Engineer to help build, operate, and improve the infrastructure foundations that support computational science, data engineering, analytics, and enterprise business operations across RevMed. This role will partner with scientific, G&A, data, security, and IT stakeholders to deliver reliable, secure, scalable compute and platform services. The ideal candidate brings deep infrastructure experience, strong operational judgment, and the ability to translate scientific and business computing needs into practical, reusable platform patterns. What You’ll Do: Design, operate, and improve secure cloud infrastructure for R&D and scientific computing workloads. Build reusable infrastructure patterns for compute, storage, networking, identity, secrets management, and observability. Use Infrastructure as Code, primarily Terraform, to standardize provisioning and change management. Support high-throughput and scientific compute environments, including HPC and scheduler-based workloads. Enable reproducible compute patterns using Linux, containers, registries, and automated deployment workflows. Partner with data and ML teams on infrastructure for dataset staging, training workflows, batch inference, and platform reliability. Operate and improve Databricks infrastructure, including workspace patterns, cluster policies, networking, identity, secrets, governance integrations, and cost-aware operations. Support data platform infrastructure for scientific, analytics, and G&A use cases, including secure access patterns, governance integrations, and scalable storage. Improve operational practices such as monitoring, incident response, runbooks, capacity planning, and cost awareness. Collaborate cross-functionally with scientists, data engineers, security, and IT to deliver practical platform solutions. Mentor others and contribute to standards, documentation, and reusable patterns for scientific infrastructure. Required Skills, Experience and Education: BS in Computer Science, Engineering, or a related technical field, or equivalent practical experience. 8+ years of relevant experience in cloud infrastructure, platform engineering, systems engineering, DevOps/SRE, scientific computing, or related technical roles. Strong experience operating production infrastructure in AWS, Azure, or another major cloud platform. Strong experience with Terraform or comparable Infrastructure as Code practices. Practical experience with Linux, networking fundamentals, system troubleshooting, and operational support. Experience with CI/CD, version control, peer review, testing, and change management practices. Experience supporting containerized workloads using Docker or similar technologies. Demonstrated ability to work independently on complex technical problems and collaborate across teams. Preferred Skills: Experience supporting HPC or high-throughput compute environments, including Slurm or similar schedulers. Experience supporting scientific computing, computational chemistry, computational biology, or data-intensive R&D workflows. Experience operating Databricks infrastructure, data platform services, or governed analytics environments. Experience with cloud security, identity, least privilege access, auditability, and regulated environments. Familiarity with workflow tools such as Nextflow, Snakemake, Airflow, cloud batch services, or Kubernetes. Experience building reusable platform patterns, documentation, and self-service infrastructure capabilities. What Success Looks Like Scientific, data, and G&A teams can run scalable workflows reliably using clear, supported infrastructure patterns. Databricks environments are secure, governed, reliable, cost-aware, and aligned with enterprise platform standards. Infrastructure changes are reproducible, reviewed, tested, documented, and safely deployed. Cloud and scientific compute environments are reliable, observable, secure, and cost-aware. Platform patterns reduce one-off support needs and improve consistency across teams. Cross-functional partners view this role as a trusted technical owner for scientific infrastructure. #LI-Hybrid #LI-YG1 We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.

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