Scientist, Computational & Digital Pathology (AcelaBio)

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  "last_changed_at": "2026-05-29T07:01:33.822Z",
  "active_status": "active"
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  "language": "en",
  "location": {
    "raw": "San Diego, California",
    "city": "San Diego",
    "region": "CA",
    "country": "United States",
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    "confidence": 0.85
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  "inferred_at": "2026-06-21T07:57:56.563Z",
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      "raw": "San Diego, California",
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      "region": "CA",
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    "countries": [
      "United States"
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  "remote_policy": "hybrid",
  "salary_period": "year",
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  "salary_currency": "USD"
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{
  "lists": [
    {
      "text": "Responsibilities",
      "content": "\n<li><strong>What you'll be doing: </strong></li>\n\n<div>\n<div><strong>Assay Development, Image Analysis (Core Focus):</strong></div>\n\n<li>Design, develop, optimize, and validate immunostaining assays including single-plex IHC,&nbsp;multiplex immunofluorescence (mIF), in situ hybridization (ISH), and spatial biology platforms.</li>\n<li>Define analytical endpoints, scoring strategies, and QC metrics aligned with assay performance requirements.</li>\n<li>Develop, validate, and maintain image analysis pipelines using platforms such as Visiopharm,&nbsp;HALO, or equivalent software.</li>\n<li>Build and implement AI/machine learning algorithms for tissue segmentation, cell phenotyping,&nbsp;and biomarker quantification.</li>\n<li>Ensure traceability, reproducibility, and thorough documentation of all analysis workflows.</li>\n<li>Contribute to assay validation documentation, analytical reports, and regulatory-aligned&nbsp;deliverables.</li>\n<li>Partner with histotechnicians to support hands-on assay troubleshooting and knowledge&nbsp;transfer</li>\n\n<strong>Scientific Leadership &amp; Client Engagement;</strong></div>\n\n<li>Serve as a scientific interface for sponsors, participating in protocol reviews, study design discussions, and data review meetings.</li>\n<li>Provide expert guidance on biomarker study design incorporating omics and non-omics endpoints.</li>\n<li>Prepare and review project plans, analysis plans, study reports, abstracts, and technical manuscripts.&nbsp;</li>\n<li>Deliver clear, scientifically rigorous data visualizations, analyses, and summaries tailored to sponsor audiences&nbsp;</li>\n\n<div>&nbsp;</div>\n<div><strong>Business Development and Innovation:</strong></div>\n\n<li>Support RFP responses, project pricing, protocol review, and bid defense activities.</li>\n<li>Contribute to the development of sales, marketing, and promotional scientific content.</li>\n<li>Drive continuous improvement of our computational pathology, spatial biology, and translational&nbsp;research service offerings.</li>\n<li>Participate in capability development and functionality reviews to expand the AcelaBio service&nbsp;portfolio.</li>\n"
    },
    {
      "text": "Qualifications",
      "content": "\n<li>\n<p><strong>Education and Experience:</strong></p>\n\n</li><li>Graduate degree (M.Sc. or Ph.D.) in a relevant scientific discipline (pathology, cell biology,&nbsp;molecular biology, biomedical engineering, or related field).</li>\n<li>7 or more years of hands-on experience in IHC/IF assay development and image analysis in a&nbsp;CRO, biopharma, or regulated research environment.</li>\n<li>Demonstrated experience building image analysis algorithms or pipelines in platforms such as&nbsp;Visiopharm, HALO, or similar.</li>\n<li>Exposure to spatial biology platforms (e.g., 10x Visium, Xenium, Akoya PhenoCycler) is a strong&nbsp;asset.</li>\n\n\n\n\n<li><strong>Technical Skills &amp; Competencies</strong>:\n\n</li><li>Deep practical knowledge of chromogenic IHC and multiplex immunofluorescence, including&nbsp;antibody selection, panel design, optimization, and troubleshooting.</li>\n<li>Proficiency in digital pathology image analysis and quantitative biomarker readout strategies.</li>\n<li>Familiarity with AI/ML approaches for histopathology applications.</li>\n<li>Understanding of regulatory and GxP expectations for assay validation documentation.</li>\n<li>Scientific rigor and meticulous attention to detail.</li>\n<li>Ability to communicate complex scientific concepts clearly to both technical and non-technical&nbsp;stakeholders.</li>\n<li>Strong written and oral English communication skills; comfortable presenting at client meetings&nbsp;and scientific forums.</li>\n<li>Ability to manage multiple projects in a fast-paced, client-driven environment.</li>\n<li>Collaborative mindset with the ability to work across laboratory, scientific, and operational&nbsp;functions.</li>\n\n\n"
    }
  ],
  "country": "US",
  "createdAt": 1769125127574,
  "updatedAt": null,
  "categories": {
    "team": "AcelaBio",
    "location": "San Diego, California",
    "commitment": "Full-time, Permanent",
    "department": "AcelaBio",
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      "San Diego, California"
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