Director of Cellular Immunotherapy GMP Manufacturing

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are looking for a leader to head the Manufacturing of Cellular Immunotherapies in Cell and Gene Therapy Operations. This role reports to the Vice President of Cell and Gene Therapy Operations / Director of the Center for Bioinnovation and Manufacturing. COH has a mission to transform the future of cancer care. In support of this mission, COH has over 20+ years of experience in GMP production of Cell and Gene Therapies holding >120 active INDs and supported by an 80+ person GMP team. The new Director will oversee a Manufacturing team of >15 people that focuses primarily on autologous production of >60 CAR-T therapies per year in support of early clinical trials. Additional relevant areas of expertise are manufacturing of TILs and CAR-NK. As a successful candidate you will: · Lead and manage a high-performing team responsible for cGMP manufacturing of cellular immunotherapy products. · Ensure execution of manufacturing processes that meet rigorous safety, quality, and compliance standards. · Oversee GMP manufacturing logistics, including scheduling, resource allocation, and throughput optimization. · Troubleshoot and resolve issues, identify root causes, and implement process improvements with clear communication to senior leadership and project PIs. · Develop and monitor KPIs for productivity, efficiency, and compliance. · Drive continuous improvement initiatives, leveraging advanced technologies and best practices. · Ensure adequate staffing, facilities, equipment, and documentation to meet evolving priorities and capacity needs. · Collaborate with internal stakeholders to align manufacturing operations with institutional goals. · Partner with Project Management to develop budgets for internal and external projects. · Recruit, train, and mentor team members, fostering professional growth and career development. · Establish organizational structure, policies, and production schedules to support operational excellence. · Promote a culture of collaboration, accountability, and innovation Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are looking for a leader to head the Manufacturing of Cellular Immunotherapies in Cell and Gene Therapy Operations. This role reports to the Vice President of Cell and Gene Therapy Operations / Director of the Center for Bioinnovation and Manufacturing. COH has a mission to transform the future of cancer care. In support of this mission, COH has over 20+ years of experience in GMP production of Cell and Gene Therapies holding >120 active INDs and supported by an 80+ person GMP team. The new Director will oversee a Manufacturing team of >15 people that focuses primarily on autologous production of >60 CAR-T therapies per year in support of early clinical trials. Additional relevant areas of expertise are manufacturing of TILs and CAR-NK. As a successful candidate you will: · Lead and manage a high-performing team responsible for cGMP manufacturing of cellular immunotherapy products. · Ensure execution of manufacturing processes that meet rigorous safety, quality, and compliance standards. · Oversee GMP manufacturing logistics, including scheduling, resource allocation, and throughput optimization. · Troubleshoot and resolve issues, identify root causes, and implement process improvements with clear communication to senior leadership and project PIs. · Develop and monitor KPIs for productivity, efficiency, and compliance. · Drive continuous improvement initiatives, leveraging advanced technologies and best practices. · Ensure adequate staffing, facilities, equipment, and documentation to meet evolving priorities and capacity needs. · Collaborate with internal stakeholders to align manufacturing operations with institutional goals. · Partner with Project Management to develop budgets for internal and external projects. · Recruit, train, and mentor team members, fostering professional growth and career development. · Establish organizational structure, policies, and production schedules to support operational excellence. · Promote a culture of collaboration, accountability, and innovation Your qualifications should include: · Bachelor’s degree in biological sciences, engineering, or related field (Masters or PhD preferred). · Minimum of 5 years of experience working with human T-cells, primary human cells, immune systems or similar biological systems. · Minimum of 2 years of experience in cGMP cell therapy and/or biological product manufacturing, ideally with immunoeffector cell therapy focus. · Minimum of 2 years supervisory experience and leading teams of greater than 5 people in a highly matrixed and milestone-driven environment. · Strong understanding of CAR-T biology, including T-cell activation, cytotoxicity, and exhaustion. · Strong Interpersonal and collaboration skills to interface with external groups. · In-depth knowledge of cGMP regulations and FDA guidance for biologics and cell therapy. · Experience in regulatory documentation (e.g., FDA CMC submissions). City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE . Your qualifications should include: · Bachelor’s degree in biological sciences, engineering, or related field (Masters or PhD preferred). · Minimum of 5 years of experience working with human T-cells, primary human cells, immune systems or similar biological systems. · Minimum of 2 years of experience in cGMP cell therapy and/or biological product manufacturing, ideally with immunoeffector cell therapy focus. · Minimum of 2 years supervisory experience and leading teams of greater than 5 people in a highly matrixed and milestone-driven environment. · Strong understanding of CAR-T biology, including T-cell activation, cytotoxicity, and exhaustion. · Strong Interpersonal and collaboration skills to interface with external groups. · In-depth knowledge of cGMP regulations and FDA guidance for biologics and cell therapy. · Experience in regulatory documentation (e.g., FDA CMC submissions). City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE .

{
  "content_hash": "be05dea936cec90465870fa1bcd358750a8b49ce8cec120a707a17573aa8c3f6",
  "source_hash": "79f1497caf897d28da3f9f3dd648a6973df25ffda063ff67166059c35c220bcf",
  "last_changed_at": "2026-06-05T03:57:05.963Z",
  "active_status": "active"
}

{
  "language": "en",
  "location": {
    "raw": "United States-California-Duarte",
    "city": "Duarte",
    "region": "CA",
    "country": "United States",
    "is_remote": false,
    "confidence": 0.95
  },
  "salary_max": null,
  "salary_min": null,
  "inferred_at": "2026-06-06T13:45:28.181Z",
  "launch_scope": {
    "reason": "english_us_canada",
    "included": true,
    "language": "en",
    "location": {
      "raw": "United States-California-Duarte",
      "city": "Duarte",
      "region": "CA",
      "country": "United States",
      "is_remote": false,
      "confidence": 0.95
    },
    "countries": [
      "United States"
    ]
  },
  "remote_policy": null,
  "salary_period": null,
  "workplace_type": null,
  "salary_currency": null
}

{}

{
  "list_job": {
    "raw": {
      "draft": false,
      "jobId": "224385",
      "column": [
        "Director of Cellular Immunotherapy GMP Manufacturing",
        "[\"United States-California-Duarte\"]",
        "Jan 13, 2026"
      ],
      "hotJob": false,
      "contestNo": "10033169",
      "toReApply": false,
      "linkedColumn": 0,
      "addedToJobCart": false,
      "alreadyAppliedOn": false,
      "locationsColumns": [
        1
      ]
    },
    "jobId": "224385",
    "title": "Director of Cellular Immunotherapy GMP Manufacturing",
    "legacy": false,
    "category": null,
    "schedule": null,
    "contestNo": "10033169",
    "detailUrl": "https://aa067.taleo.net/careersection/sci_rsrch/jobdetail.ftl?job=224385&lang=en",
    "locations": [
      "United States-California-Duarte"
    ],
    "postingDate": "Jan 13, 2026"
  },
  "detail_meta": {
    "url": "https://aa067.taleo.net/careersection/sci_rsrch/jobdetail.ftl?job=224385&lang=en",
    "http_status": 200,
    "content_type": "text/html;charset=UTF-8",
    "response_bytes": 141168
  },
  "detail_errors": [],
  "detail_values_count": 42
}