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HomeCompaniesLila SciencesPrincipal / Senior Principal, Security Architect

Principal / Senior Principal, Security Architect

Lila Sciences · San Francisco, CA USA · Active · $204,000–$310,000 / year · Greenhouse

Job facts

FieldValue
CompanyLila Sciences
TitlePrincipal / Senior Principal, Security Architect
Normalized title-
Department / teamBusiness Operations
LocationSan Francisco, CA, United States
Work model-
Employment type-
Salary$204,000–$310,000 / year
Statusactive
ATS providerGreenhouse
Posted / first seen2026-02-11 / 2026-05-29
Changed / last seen2026-05-29 / 2026-06-06

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Company jobsActive postings from Lila Sciences.Open
Company breakdownsRole, location, ATS, and work model facets for this company.Open
ATS provider jobsActive postings observed through Greenhouse.Open
Provider filtered searchThe same provider as a filtered job collection.Open
City jobsActive postings in San Francisco.Open
Department jobsActive postings in Business Operations.Open
Lifecycle eventsOpen, update, close, and reopen events for this posting.Open
Original postingCanonical source or apply URL captured from the ATS.Open

Linked records

CompanyLila Sciences
Sourcea1e67975-fd33-4f8d-940f-2dbc2480c450
ATS providerGreenhouse

Description

Your Impact at LILA We’re looking for a Principal Security Architect to lead the security architecture for cloud applications operating at FedRAMP IL5 and IL6, while also shaping enterprise-wide security architecture and engineering. This is a hands-on leadership role—your work will directly enable secure product delivery at speed. You’ll lead the design, implementation, and authorization of FedRAMP IL5/IL6 systems, then scale that success by building reusable security platforms, patterns, and practices across the organization. What You'll Be Building You will define and deliver secure cloud architectures that meet the highest federal standards while staying practical and engineer friendly. Your designs will become the foundation for multiple systems and scale across teams and environments. FedRAMP IL5 / IL6 security architectures co-owned with Application Architects and applied across multiple systems Deployable security designs grounded in NIST 800-53 Rev. 5, DoD Cloud SRG (IL5/IL6), and FedRAMP Core security building blocks, including: Identity, credential, and access management (ICAM) Network segmentation, trust boundaries, and secure data flows Encryption, key management, and secrets handling Zero Trust architecture (NIST 800-207) implemented in production—not just documented Reusable security platforms and patterns, including: IAM and access control Secrets management and key lifecycle Logging, monitoring, and detection Secure CI/CD and Infrastructure as Code Enterprise reference architectures supporting both FedRAMP and non-FedRAMP systems Compliance-aware designs that minimize authorization scope through control inheritance, reuse, and standardization Automated compliance evidence pipelines that reduce manual effort and improve audit readiness Security-by-design integrations embedded into product engineering and cloud infrastructure Architectural support for resilience and response, including threat modeling, risk assessment, incident response, and forensic readiness What Success Looks Like Security controls are designed once and reused across applications and platforms Compliance evidence is automated, repeatable, and scalable Engineering teams adopt security patterns naturally, without friction Security architecture accelerates delivery instead of slowing it down This role is for someone who wants to build durable, reusable security architecture that scales beyond one system—and enables high-assurance cloud delivery at speed. This is not a policy-only or governance-only position. What You’ll Need to Succeed You bring deep, hands-on experience designing and delivering secure cloud systems in highly regulated environments. You’re comfortable translating complex requirements into scalable architecture and guiding teams through delivery. 8+ years in cybersecurity, security architecture, or security engineering Proven, hands-on delivery of FedRAMP IL5 and/or IL6 systems, from design through authorization Strong working knowledge of: NIST 800-53 Rev. 5 DoD Cloud Computing SRG (IL5/IL6) FedRAMP authorization and ATO processes Cloud security architecture experience in AWS GovCloud Experience securing cloud-native platforms, including: Container orchestration (EKS, AKS, OpenShift) CI/CD pipelines and Infrastructure as Code Ability to explain control intent and risk tradeoffs, not just map requirements to controls Compensation We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact. U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market. Expected Base Salary Range $204,000 — $310,000 USD About LILA Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves. LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai. Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply. We’re All In Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy . A Note to Agencies Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Full job record

Job IDb22bdb609e3b115d44869b4162301826d012e485
Org IDffee088c-1794-41ee-9ae7-d3e130389319
Source IDa1e67975-fd33-4f8d-940f-2dbc2480c450
Board IDa1e67975-fd33-4f8d-940f-2dbc2480c450
Providergreenhouse
Provider Job Key4121314009
TitlePrincipal / Senior Principal, Security Architect
Normalized Title
Statusactive
Activeyes
Location TextSan Francisco, CA USA
DepartmentBusiness Operations
Team
Employment Type
Workplace Type
Remote Policy
CountryUnited States
RegionCA
CitySan Francisco
Salary RawSalary Range $204,000 — $310,000 USD About LILA Lila Sciences is building Scientific Superintel
Salary Min204,000
Salary Max310,000
Salary CurrencyUSD
Salary Periodyear
Source URLhttps://job-boards.greenhouse.io/lilasciences/jobs/4121314009
Apply URLhttps://job-boards.greenhouse.io/lilasciences/jobs/4121314009
First Seen At2026-05-29 23:01:25Z
Last Seen At2026-06-06 07:34:08Z
Last Checked At2026-06-06 07:34:08Z
Last Changed At2026-05-29 23:01:25Z
Inactive At
Source Posted At2026-02-11 20:48:32Z
Source Updated At2026-05-14 21:07:30Z
Raw Payload Uris3://job-postings-prod-raw-590183727216/raw/provider=greenhouse/board=lilasciences/date=2026-06-06/2026-06-06T07-34-07-839Z-8910748710b03f2325a47d95b68801d1b5e36c899ac6edbc67e980d6caead799.json
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Parsed Structured
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Extensions
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