Scientist I, Biologics Drug Substance Development, Cell Culture Development

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          "text": "<p>The Cell Culture Development Group in South San Francisco, CA is seeking a Scientist I to join a talented and collaborative team to develop cell culture processes for GMP applications.</p><p>In this position, you will perform cell culture process development, scale-up, and technology transfer activities in a well-supported and dynamic environment to help advance novel biotherapeutics into human clinical studies.&#xa0;</p><p><strong>KEY RESPONSIBILITIES:</strong></p><p>&#xa0;</p><ul><li>Perform inoculum expansion and cell bank generation</li><li>Execute cell culture experiments using Ambr250 and 2L bioreactors</li><li>Perform pilot scale material generation using 50L, 200L and 500L single use bioreactors</li><li>Execute small scale and pilot scale depth filtration and centrifugation primary recovery processes</li><li>Perform tech transfer of Master cell bank generation, cell culture and primary recovery processes to the GMP manufacturing facilities</li><li>Provide person-in-plant support at the GMP manufacturing facility</li><li>Perform cell culture experiments to optimize N-1 perfusion processes as well as intensified fed-batch processes</li><li>Represent the cell culture development group for pipeline projects in cross-functional meetings and collaborate closely with cell line, purification, analytical and formulation development leads to meet project timelines</li><li>Author and review technical reports, GMP campaign summary reports, and relevant sections in regulatory filings</li><li>Proactively identify and implement opportunities to optimize platform processes and deepen process understanding</li><li>Present scientific findings at internal or external conferences</li></ul><p>Collaborate effectively with colleagues to promote a positive and efficient laboratory environment, and actively contribute ideas to enhance lab workflows and practices</p>",
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          "text": "<p><strong>Required</strong></p><ul><li>Scientific degree in chemical engineering, bioengineering, biotechnology, or a related field. A minimum of 2 years for M.S. or 5 years for B.S. graduates</li><li>Proficient in aseptic techniques</li><li>Experience in developing and executing mammalian suspension cell culture processes in shake flasks, Ambr250 and 2L bioreactors</li><li>Strong understanding of mammalian cell and molecular biology and cell culture bioprocess engineering concepts&#xa0;</li><li>Strong attention to detail; active and quick learner; able to change courses quickly as needed, raises the bar and is never satisfied with the status quo; opens to suggestions and embraces the ideas of others; actively builds relationships with others</li><li>Experience in technical report authoring and reviewing</li><li>Proficient with Microsoft Office software (Word, Excel, and PowerPoint) and statistical modelling software such as JMP</li></ul><p><strong>Preferred:&#xa0;</strong></p><ul><li>Experience in perfusion technology, especially Alternating Tangential flow filtration (ATF) at bench</li><li>Experience in pilot scale operations including 50L, 200L, 500L Single-use systems, and harvest operations</li></ul><p>&#xa0;</p>",
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          "text": "<p><strong>About AbbVie</strong></p><p>AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at&#xa0;<a href=\"http://www.abbvie.com/\" rel=\"noopener noreferrer\">www.abbvie.com</a>. Follow @abbvie on&#xa0;<a href=\"https://www.linkedin.com/company/abbvie/\" rel=\"noopener noreferrer\">LinkedIn,</a>&#xa0;<a href=\"https://www.facebook.com/AbbVieGlobal/\" rel=\"noopener noreferrer\">Facebook</a>,&#xa0;<a href=\"https://www.instagram.com/abbvie/\" rel=\"noopener noreferrer\">Instagram</a>,&#xa0;<a href=\"https://twitter.com/abbvie\" rel=\"noopener noreferrer\">X</a>&#xa0;and&#xa0;<a href=\"https://www.youtube.com/user/AbbVie\" rel=\"noopener noreferrer\">YouTube.</a></p>",
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          "text": "<p>Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or&#xa0;local law:&#xa0;​</p><ul><li><p>The compensation range described below is the range of possible base pay compensation that the Company&#xa0;believes in&#xa0;good faith it will pay for this role at the time&#xa0;of&#xa0;this posting based on the job grade for this position.&#xa0;Individual&#xa0;compensation paid within this range will depend on many factors including geographic location,&#xa0;and&#xa0;we&#xa0;may&#xa0;ultimately&#xa0;pay&#xa0;more or less than the posted range. This range may be&#xa0;modified&#xa0;in the&#xa0;future.&#xa0;​</p></li><li><p>We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),&#xa0;medical/dental/vision&#xa0;insurance and 401(k) to eligible&#xa0;employees.​</p></li><li><p>This job is eligible to&#xa0;participate&#xa0;in our short-term incentive&#xa0;programs.&#xa0;​</p></li></ul><p>Note: No amount of pay&#xa0;is considered to be&#xa0;wages or compensation until such amount is earned, vested, and&#xa0;determinable.&#xa0;The amount and availability of any&#xa0;bonus,&#xa0;commission, incentive, benefits, or any other form of&#xa0;compensation and benefits&#xa0;that are allocable to a particular employee&#xa0;remains&#xa0;in the Company's sole&#xa0;and&#xa0;absolute&#xa0;discretion unless and until paid and&#xa0;may be&#xa0;modified&#xa0;at the Company’s sole and absolute discretion, consistent with&#xa0;applicable law.&#xa0;​</p><div sr-tagline=\"\"></div><p>AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.&#xa0;</p><p>US &amp; Puerto Rico only - to learn more, visit&#xa0;<a href=\"https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html\" rel=\"noopener noreferrer\">https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html</a></p><p>US &amp; Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:</p><p><a href=\"https://www.abbvie.com/join-us/reasonable-accommodations.html\" rel=\"noopener noreferrer\">https://www.abbvie.com/join-us/reasonable-accommodations.html</a></p>",
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