Sr. Scientist - Small Molecule

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    "ExternalDescriptionStr": "<p><strong>How You’ll Contribute:</strong></p>\n<p>This position is within the Analytical Development team of the Applied Research department.&nbsp; This role focuses on developing, validating, and transferring analytical methods to support small and large molecule drug development and formulations from early-stage clinical studies up to commercialization.</p>\n<p>The position will establish, coordinate and monitor analytical related activities both internally and with CROs and CMOs to ensure quality and timeliness of projects.&nbsp;The position also involves overseeing stability studies and conducting trending analysis for drug substance and drug product.&nbsp;The ideal candidate works effectively and collaboratively with cross-functional groups and will represent as analytical lead on CMC project teams.&nbsp;This position is expected to communicate data both verbally at group meetings and through written documents and reports and be able to comfortably multitask across projects and disciplines.</p>\n<p><strong>What You’ll Do:</strong></p>\n<ul>\n <li>Provides technical expertise to design, conduct, and implement analytical and development activities for large and small molecules to support all stages of drug development.&nbsp;</li>\n <li>Troubleshoots and solves technical challenges in a timely manner and ensures generation of high-quality scientific data.&nbsp;</li>\n <li>Evaluates and interprets data from release and stability studies and provides scientific conclusions.&nbsp;</li>\n <li>Maintains expertise in cutting-edge assay technologies used for the characterization of drug delivery systems for drug release, potency, stability, impurity testing and aggregation profile.</li>\n <li>Prepares high quality experimental protocols and technical reports in support of regulatory submissions. Supports authoring appropriate portions of CMC section of INDs, NDAs and prepares responses to regulatory questions.&nbsp;</li>\n <li>Represents as analytical lead on CMC project teams, provides scientific solutions and contributes to team discussions. Support QC department with establishing robust methods, product specifications, method validations and method transfers.&nbsp;</li>\n <li>Proactively develops and maintains knowledge in current analytical sciences and investigates new technologies, recommends and implements innovative techniques to the team.</li>\n</ul>\n<p><strong>How You’ll Get There:</strong></p>\n<ul>\n <li>Strong hands-on knowledge of chromatographic theory and technology.</li>\n <li>Working knowledge of HPLC, UPLC, GC, LC-MS, UV/Vis, Dissolution and other common analytical techniques used to determine potency, purity, and in-vitro performance of drug substance and drug product.</li>\n <li>Ability to perform investigations and troubleshoot technical problems at all stages of development, being detail oriented are important attributes.&nbsp;</li>\n <li>Excellent written and verbal communication skills; prior experience working within regulated environments (e.g., GMP, ICH, FDA) to ensure analytical activities meet compliance standards and support regulatory filings and inspections.&nbsp;</li>\n <li>Strong ability and knowledge to develop, validate and transfer methods.&nbsp;Experience in oversight of stability studies, conducting trend analysis and interpreting data.&nbsp;</li>\n <li>Ability to work within a diverse workforce, scientific participation and collaboration with colleagues in industry, academia and regulatory agencies.</li>\n <li>Experience in interacting with pharmaceutical CROs and CMOs and providing guidance.&nbsp;</li>\n <li>Project management skills including the ability to manage multiple projects and evaluate project resource requirements. Strong knowledge of Quality systems, Drug Product Manufacturing and Validation.&nbsp;</li>\n <li>Good knowledge of drug development and product regulations.</li>\n <li>Ph.D. (with 3+ years) or M.S. (8+ years) in analytical chemistry, pharmaceutical chemistry, pharmaceutical sciences, or related scientific field and 3+ years of pharmaceutical industry experience in small or large molecule analytical development, and&nbsp;</li>\n <li>Salary Range: 97900. - 122400. plus rich package of bonus, benefits and more!<br><br>\n  &nbsp;</li>\n</ul>\n<div>\n #GKOSUS\n</div>",
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    "CorporateDescriptionStr": "<p style=\"margin:0in;font-style:normal;font-weight:400\"><b>Generous. Innovative. Leadership-driven. Family-oriented. Socially responsible.&nbsp;</b></p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">Founded in 1998, Glaukos Corporation is an ophthalmic pharmaceutical and medical technology company focused on developing and commercializing novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases.</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">Our mission at Glaukos is to truly transform vision by pioneering novel, dropless therapies that can meaningfully advance the standard of care and improve the lives of patients suffering from chronic, sight-threatening eye diseases.&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">Innovation is at the core of everything we do, and we are resolute in our commitment to challenge conventional thinking with new treatment alternatives that are supported by real science, robust clinical evidence, and an unrelenting focus on patients.&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">Our constant pursuit of game-changing technologies that disrupt legacy treatment paradigms is encapsulated in the Glaukos mantra “We’ll Go First,” which articulates our willingness to take chances, our determination to forge new ground, and our commitment to continuous improvement in all that we do.&nbsp;&nbsp;&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">Our company completed an initial public offering in June of 2015, and our shares are traded on the New York Stock Exchange under the ticker symbol “GKOS”. Our global headquarters is in Aliso Viejo, California with additional locations in San Clemente, California, and Burlington, Massachusetts.</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\"><b>Glaukos Corporation is an Equal Opportunity/Affirmative Action Employer</b>. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.&nbsp;</p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\"><br></p>\n<p style=\"margin:0in;font-style:normal;font-weight:400\">All offers of employment are contingent upon the successful completion of a background check, including successfully passing a drug screen, based on the position and local regulations.</p>",
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