Senior Mechanical Design Engineer, Automation (Contract)

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    "datePosted": "2026-01-14T05:00:00.000Z",
    "description": "<h2>Job Description</h2>\n<p>Are you ready to revolutionize Cell & Gene Therapy? Join us in shaping the future of therapeutics! We are seeking a Senior Mechanical & Automation Engineer in our journey of developing cutting-edge manufacturing solutions for Casgevy—a first-of-its-kind therapy transforming the treatment of Sick Cell Disease and Beta Thalassemia. In this role, you will be at the forefront of automating complex processes in one of the most dynamic and rapidly evolving fields in biotechnology. By leveraging your expertise in mechanical engineering and automation, you will play a pivotal role in streamlining manufacturing, enhancing manufacturing reliability, and scaling life-saving therapies to reach patients faster. You will work with a passionate team of scientists, engineers, and innovators, all united by a shared mission: to push the boundaries of what’s possible in Cell & Gene Therapy. This role reports to the Associate Director of Automation, Equipment, and Processes.</p>\n<p> </p>\n<p><strong>Key Responsibilities:</strong></p>\n<ul>\n <li>Development of industrial machinery and automation from concept through commercial deployment.</li>\n <li>Manage the evaluation and selection of new equipment/technologies or modifications to existing systems required for scale up.</li>\n <li>Mechanical Design and integration, including, but not limited to robotics, single-use sets, single-use set cartridges, conveyors, AGV/AMRs, cam-followers, peristaltic pumps, pinch valves, MFCs, Solenoid valves, and process analytical technologies, and more.</li>\n <li>Mechanical Design Analysis, including, but not limited to kinematic design & analysis, dynamic analysis, stress analysis, tolerance stack analysis, mechanism design, cycle time calculation, utilization calculations, and cam-follower design.</li>\n <li>Aseptic and GMP design. Design for compatibility with cleaning and sterilization. Single Use Set Design experience.</li>\n <li>Interface and collaborate with controls resources for joint electro-mechanical designs.</li>\n <li>Manage vendors and perform design reviews, FATs, and SATs. Support validation activities.</li>\n <li>Create a scale up plan from concept through commercial equipment deployment.</li>\n <li>Provide support to non-engineering Staff, including those from R&D and Manufacturing, to ensure successful technology transfer and continuous improvement.</li>\n <li>Support optimization and improvement in equipment/systems/processes.</li>\n <li>Establishes equipment documentation, including parts lists, mechanical drawings, and assembly drawings. Provides engineering change documentation as appropriate.</li>\n <li>Statistically characterizes equipment performance and implements designs to ensure repeatability and consistency.</li>\n <li>Design and manage vendor design of 3D CAD models. Collaborate with vendors to produce prototype and production parts.</li>\n <li>Create Equipment layouts in AutoCAD and/or Revit.</li>\n <li>Create drawings to ASME Y14.5M-200977. Understand and apply other respective standards within machine design, including ANSI and ISO standards.</li>\n <li>Provide hands-on troubleshooting, equipment, and manufacturing assistance in support of a rapid development cycle and manufacturing sustainability.</li>\n <li>Execute assigned duties on time and within budget; proactively communicate delays and other issues to relevant stakeholders.</li>\n <li>Comply with all regulatory, corporate, and Quality System policies. Support Deviation Management, CAPA, and Change Control activities, as required.</li>\n <li>Performs other duties as assigned.</li>\n</ul>\n<p> </p>\n<p><strong>Required Qualifications:</strong></p>\n<ul>\n <li>BS or MS in engineering or another relevant discipline.</li>\n <li>5+ years of experience working within an automation development environment (pharmaceutical, cGxP preferred). Experience with cell & gene therapy is highly desirable.</li>\n <li>Experience working with a variety of automation hardware, including but not limited to, custom-fabricated mechanical components, cam systems, linkages, index and dwell machines, cartesian robots, SCARA robots, end of arm tooling, and dip coating.</li>\n <li>Experience developing single use sets.</li>\n <li>Understanding of cGxP principles and practices and familiarization with ISO 13485, ISO 14971, and 21CFR820 is a plus. Knowledge of global cGMP requirements governing device or combination products.</li>\n <li>Experience with 3D CAD software, preferably with Solidworks.</li>\n <li>Experience troubleshooting industrial automation.</li>\n <li>A strong understanding of statistical principles is required, as are strong technical writing and presentation skills.</li>\n <li>Must be able to work independently with adequate supervision, multi-task, and support several projects simultaneously.</li>\n <li>Sense of urgency, ability to act/escalate promptly, and transparently communicate issues to involved stakeholders and management.</li>\n <li>Must demonstrate strong interpersonal, presentation, and teamwork skills.</li>\n <li>This is a 5 days a week role, requiring 3 days onsite per week at our Boston and Rhode Island offices. </li>\n</ul>\n<h2>Pay Range</h2>\n<p>$75/hr.- $90/hr.</p>\n<h2>Shift/Hours</h2>\n<p>Monday-Friday</p>\n<h2>Requisition Disclaimer</h2>\n<p>This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third- party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements</p>\n<p> </p>\n<p>By applying for this position, you agree to the Atrium Terms and Conditions and you direct Atrium to share your application materials, which may include your CV/Resume, email address or phone number, with Vertex. For more information on how Vertex handles your personal data related to your job application, please see Vertex’s Careers Privacy Notice.   Agreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners</p>\n<p>(collectively, “Atrium Alerts”). Atrium Alerts may be sent by email, phone, or text message. Your personal information will be safely stored within the Atrium & Vertex databases. Atrium does not sell your personal information to third parties. Text message and data rates may apply. To OPT OUT of text messaging or to modify your communication preferences for Atrium Alerts at any time, please contact Atrium at [email protected].</p>\n<p> </p>\n<p>If you do not agree with the Atrium Terms and Conditions, you can still complete your application for this position by emailing your resume to our team at [email protected]. Please include the job title in the subject of your email.</p>\n<p> </p>\n<p><strong>No C2C or Third-Party Vendors</strong></p> ",
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