Manufacturing Hardware Engineer / Life Cycle Engineer

At Alamar, we are passionate about enabling our customers to make scientific discoveries that translate into clinical outcomes and benefit patients. Our team is growing quickly as we develop innovative approaches to measure critical protein biomarkers from liquid samples that can enable the earliest possible detection of disease. We believe the next frontier in biology is enabled by measuring proteins at higher sensitivity in highly multiplexed assays at the push of a button, which is something only Alamar can do. As we build our team, we seek collaborative, driven, intellectually curious people committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe this enables the kind of breakthrough thinking that will accelerate our mission. We are seeking a hands-on, detail-oriented Hardware Engineer / Life Cycle Engineer to support automated bioassay platforms and maintain production processes, systems and machinery to ensure efficient, quality product manufacturing. Candidate should have a strong focus on Hamilton liquid handling systems used in complex bioconjugation workflows. This role is critical to ensuring instrument reliability, minimizing downtime, and supporting manufacturing through effective troubleshooting, maintenance, and lifecycle management. The ideal candidate combines technical depth with strong problem-solving skills and thrives in a fast-paced, dynamic environment. Core Responsibilities Perform advanced troubleshooting on Hamilton liquid handling systems supporting complex bioconjugation assays, including root cause analysis and issue resolution. Execute and document routine maintenance, calibration, and repair of Hamilton instruments to ensure optimal performance and compliance. Lead and support root cause investigations for process deviations, equipment failures, and manufacturing issues; implement corrective and preventive actions (CAPA). Develop, maintain, and track preventive maintenance (PM) schedules across automation platforms and manufacturing equipment. Able to safely perform minor interventions on liquid handling systems with simple tools. Provide feedback to Engineering Team on equipment and automation design improvements to enhance manufacturability, reliability, and serviceability. Serve as technical liaison with automation vendors and service providers, supporting FAT/SAT, service coordination, and spare parts strategy. Author, review, and maintain equipment qualification documentation including Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ). Provide real-time support to manufacturing by triaging issues, coordinating cross-functional responses, and ensuring minimal disruption to operations. Collaborate with process development, quality, and manufacturing teams to improve system robustness and assay performance. May author new standard operating procedures (SOPs) and provide training to operations team. Support lifecycle engineering activities, including equipment onboarding, validation, upgrades, decommissioning, and continuous improvement initiatives. Maintain organized lab environments, including basic lab operations, inventory tracking, calibration schedule and equipment readiness. Communicate effectively across teams, providing clear documentation, status updates, and technical insights. Required Qualifications Bachelor’s degree in Engineering (Mechanical, Biomedical, Electrical, or related field) or equivalent experience. 2–5+ years of experience in life cycle engineering, hardware engineering, or automation support in a laboratory or manufacturing setting. Hands-on experience with Hamilton liquid handling systems (e.g., STAR, VANTAGE) strongly preferred. Preferred Skills and Attributes Strong troubleshooting and diagnostic skills in automated systems and lab instrumentation. Experience with bioconjugation assays or similar complex bioanalytical workflows is highly desirable. Familiarity with equipment lifecycle management and GMP environments. Experience drafting and managing IQ/OQ/PQ documentation. Knowledge of preventive maintenance systems and scheduling tools. Strong critical thinking and structured problem-solving abilities. Ability to work under pressure and manage multiple priorities in a fast-paced environment. Excellent communication and documentation skills. Collaborative mindset with a strong sense of ownership and accountability. Experience in regulated environments (GMP, GLP, or ISO). Exposure to CAPA, deviation management systems, and change control processes. Basic programming or scripting experience for automation platforms is a plus. Work Environment & Physical Requirements Hands-on laboratory and manufacturing floor environment. Ability to lift and handle laboratory equipment and consumables as needed. May require occasional off-hours or weekend support for critical troubleshooting. Physical capability to move within office and lab environments and occasionally lift up to 25 lbs. The base salary range for this full-time position is $125,000 - $145,000 + bonus + equity + benefits. Our salary ranges are determined by work location, job-related skills, experience, and relevant education or training. The ranges displayed on each job posting reflect the minimum and maximum target for new hire salaries but are subject to change if the leveling of the role is adjusted. Your recruiter can share more about the specific salary range during the hiring process.

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