Principal Research Scientist I Process Development

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          "text": "<p>The PDS&amp;T Parenterals/Eye Care group is seeking a motivated Senior Scientist as a CMC drug product project lead, specifically for parenteral drug product process development and commercial site scale up and tech transfer. The candidate will independently design and execute lab studies to develop robust manufacturing processes for clinical phase and commercial products. This person will generate and analyze precise, reliable, and reproducible data in a timely manner, independently or under the direction of a more senior scientific leader. This position will be an integral part of the product development and CMC teams and is highly collaborative across functions such as analytical, process engineering, internal and external manufacturing, quality assurance, CMC regulatory affairs, &#xa0;supply chain and Operations Manufacturing Sites.</p><p>Responsibilities:</p><ul><li>Independently design and conduct critical experiments that further project goals. Implement and may innovate new experimental protocols/techniques for parenteral DP characterization studies to enable process scale up.</li><li>Interpret results and draw conclusions from own multistage experiments, note significant deviations, then suggest, design, and pursue relevant experiments.</li><li>Tech transfer activities for parenteral DP from development scale up to clinical/commercial scale.</li><li>Support drug product manufacture at GMP facilities from clinical to PPQ and commercial batches.</li><li>Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.</li><li>Authoring of comprehensive, scientifically sound reports,&#xa0;<em>e.g.</em>&#xa0;development reports or risk assessments that serve as source documents for regulatory submissions. Author portions of regulatory submissions to designated health authorities related to these reports.</li><li>Develop and maintain comprehensive project plans, timelines and development and/or scale up tech transfer strategy; technical projects at all stages of development are included, from phase II clinical through commercial.</li><li>Lead cross-functional PDS&amp;T product teams and represent the CMC team and/or PDS&amp;T in interface with PDS&amp;T leadership, other Operations functions, other AbbVie functions and external partners. Participate in or coordinate Governance efforts such as Product Performance Teams or gate reviews.</li><li>Prepare and review submissions through registration of the product as well as post-approval life-cycle management. Serve as a peer reviewer for submissions and under stand how regulatory submissions limit operational changes.</li><li>Establish and foster partnerships with key customers and counterpart functions to facilitate effective collaboration. Identify and promote best practices among PDS&amp;T CMC leads.</li><li>Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.</li></ul>",
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          "text": "<ul><li>Bachelors, Masters, or PhD in chemical engineering, pharmaceutical sciences, chemistry, pharmaceutics, or related disciplines with typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience.</li><li>Strong laboratory skills and experience focused on manufacturing process development for monoclonal antibodies, antibody constructs/conjugates or other parenteral formulations.</li><li>Scientific problem solving, experimental design, and trouble shooting skills.</li><li>Solid understanding of the various unit operations of aseptic manufacturing such as bulk freeze thaw, compounding/mixing, filtration, filling and lyophilization for liquid and lyophilized products.</li><li>Experience in laboratory documentation systems, including ELN, and demonstrated experience with technical report writing. Technical understanding and experience with small molecule products manufacturing, development, quality and analytics is required.</li><li>Knowledge and experience with FDA and global regulatory requirements for CMC issues is required.</li><li>Ability to influence internal and external experts on CMC regulatory issues, independently.</li><li>Demonstrated excellence in writing, presentation, and overall communication.</li></ul>",
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          "text": "<p><strong>About AbbVie</strong></p><p>AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at&#xa0;<a href=\"http://www.abbvie.com/\" rel=\"noopener noreferrer\">www.abbvie.com</a>. Follow @abbvie on&#xa0;<a href=\"https://www.linkedin.com/company/abbvie/\" rel=\"noopener noreferrer\">LinkedIn,</a>&#xa0;<a href=\"https://www.facebook.com/AbbVieGlobal/\" rel=\"noopener noreferrer\">Facebook</a>,&#xa0;<a href=\"https://www.instagram.com/abbvie/\" rel=\"noopener noreferrer\">Instagram</a>,&#xa0;<a href=\"https://twitter.com/abbvie\" rel=\"noopener noreferrer\">X</a>&#xa0;and&#xa0;<a href=\"https://www.youtube.com/user/AbbVie\" rel=\"noopener noreferrer\">YouTube.</a></p>",
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          "text": "<p>Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or&#xa0;local law:&#xa0;​</p><ul><li><p>The compensation range described below is the range of possible base pay compensation that the Company&#xa0;believes in&#xa0;good faith it will pay for this role at the time&#xa0;of thisposting based on the job grade for this position.&#xa0;Individual&#xa0;compensation paid within this range will depend on many factors including geographic location,and&#xa0;we&#xa0;may&#xa0;ultimately&#xa0;pay&#xa0;more or less than the posted range. This range may be&#xa0;modified&#xa0;in the&#xa0;future.&#xa0;​</p></li><li><p>We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),&#xa0;medical/dental/vision&#xa0;insurance and 401(k) to eligible&#xa0;employees.​</p></li><li><p>This job is eligible to&#xa0;participate&#xa0;in our long-term incentive&#xa0;programs.&#xa0;​</p></li></ul><p>Note: No amount of pay&#xa0;is considered to be&#xa0;wages or compensation until such amount is earned, vested, and&#xa0;determinable.&#xa0;The amount and availability of any bonus,&#xa0;commission,incentive, benefits, or any other form of&#xa0;compensation and benefits&#xa0;that are allocable to a particular employee&#xa0;remains&#xa0;in the Company's sole and&#xa0;absolute&#xa0;discretion unless anduntil paid and&#xa0;may be&#xa0;modified&#xa0;at the Company’s sole and absolute discretion, consistent with&#xa0;applicable law.</p><div sr-tagline=\"\"></div><p>AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.&#xa0;</p><p>US &amp; Puerto Rico only - to learn more, visit&#xa0;<a href=\"https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html\" rel=\"noopener noreferrer\">https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html</a></p><p>US &amp; Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:</p><p><a href=\"https://www.abbvie.com/join-us/reasonable-accommodations.html\" rel=\"noopener noreferrer\">https://www.abbvie.com/join-us/reasonable-accommodations.html</a></p>",
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