Vice President, Global Team Leader

Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation. Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs. Description of Role As Centessa continues to progress our Orexin portfolio, we are looking for a Vice President, Global Team Leader. The Global Team Leader will report to the SVP of Global Program Leadership. The successful candidate will work across multiple functions in the organization including research, pre-clinical and clinical development. This is a highly visible leadership role which will be empowered to set program strategy to advance the product to approval and beyond. Key Responsibilities Assemble, manage and lead one or more high functioning cross-functional program teams. Provide leadership through effective project management, strong goal setting, well managed team meetings and develop and oversee the integrated plan deliverables Set tone and culture of project team and relevant sub teams; set program vision and strategy, and ensure team delivers per plan Work directly with the team to identify all cross-functional dependencies and constraints and facilitate resolution activities to achieve the desired outcomes Lead the team in preparation and approval of development plans, budgets, and proposed go/no-go decision criteria for development programs Work frequently with senior management to ensure transparency is maintained and to resolve resourcing and strategic options across functions to ensure efficient design and flawless execution of the development plan to maximize the value of the program Monitor the day-to-day interactions with project core and ad hoc team members from various functions (Clinical Development, Clinical Operations, Regulatory Affairs, Research, CMC, Finance, etc.) Utilize communication abilities –both written planning and the ability to organize issues and areas that need to be elevated within the plan Interface with regulatory authorities, as well as internal and external stakeholders as required or directed (such as investors, science and physician scientist leaders, leadership or BOD) in support of the development objectives Design and implement fit-for-purpose product development teams appropriate for size and stage of program including sub-teams and/or external support when needed Work with Program Manager to prepare project timelines for all activities, resources, and costs to accomplish key milestone dates and build into the project schedule Management for one or more direct reports within program management function Qualifications Advanced professional degree in life sciences (PhD, PharmD, MD, MBA) At least 15 years’ experience in the pharmaceutical and/or biotechnology industry, the majority of which should be in team leadership, portfolio or program management 2-5 years line management experience Product development experience in CNS therapeutic area preferable, though not required Experience leading cross functional teams, particularly project teams Experience in early and late phase development, including IND/NDA filings Knowledge of nonclinical, clinical, regulatory and manufacturing aspects of drug development Experience working on small molecule development programs preferred Direct involvement with vendor/CRO management Able and willing to travel up to 25% of the time Compensation The annual base salary range for this position is $325,000.00 to $375,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge. In addition to base pay, this role is eligible for a discretionary annual bonus. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. Work Location The Vice President, Global Team Leader role is based in the US, with 20% - 25% travel. POSITION: Full-Time, Exempt EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.

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