Research Associate – tRNA and mRNA Biology

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  "lists": [
    {
      "text": "Key responsibilities for this position include: ",
      "content": "<li>Establish in vitro disease models in relevant cell types including primary neurons and glia isolated from transgenic animal models and patient-derived iPSC lines.&nbsp;</li><li>Design, troubleshoot, and execute cell-based assays in human and rodent cell lines to characterize the efficacy and safety of company's novel tRNA therapeutic leads.&nbsp;</li><li>Understand mechanism of action of lead candidates and establish assays and endpoints relevant to downstream target and disease biology. Conduct literature searches; communicate understanding in internal forums and with external collaborators and partners.&nbsp;</li>"
    },
    {
      "text": "Minimum qualifications: ",
      "content": "<li>A BS/MS in Neurobiology, Molecular/Cellular Biology, physiology, or a related discipline.&nbsp;</li><li>Extensive hands-on experience with a variety of molecular, cellular and/or physiological techniques (isolating rodent neurons and establishing primary neuronal cultures, neurite outgrowth, qPCR, western blotting, microscopy, calcium imaging, synaptic imaging, multi-electrode arrays, human IPS/ES cell culture, etc).&nbsp;</li><li>Prior experience using AAV/lentivirus in primary or iPSC-derived neurons is highly desirable.&nbsp;</li><li>Ability to master new concepts and technologies quickly and run experiments independently.&nbsp;</li><li>Scientifically rigorous, highly organized, with excellent oral and written communication skills.&nbsp;</li><li>Ability to work independently as well as collaborate with colleagues and effectively prioritize and manage multiple tasks in a fluid, fast-paced work environment&nbsp;</li>"
    }
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  "country": "US",
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    "team": "Scismic-TB",
    "location": "Cambridge, Massachusetts",
    "commitment": "Full-time",
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