Executive Director, Commercial Supply Chain

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale. Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges. Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX. Together we are moving psychiatry forward—beyond better, into a boundless future. Join us! Qualifications Bachelor’s degree (or equivalent) in science or business with 15+ years of relevant experience in pharmaceutical supply chain, including specialty product launches Expertise in strategic global supply chain, commercial manufacturing, and supplier relationship management in a virtual environment Experience forming, developing, and leading a pharmaceutical commercial supply chain function ideally in a virtual environment Significant experience leading and influencing raw material, small molecule drug substance, bulk drug product, and final packaging suppliers at multiple levels of the organization up to site leadership Proven track record and expertise in leading successful launch and supply of specialty pharmaceutical products, ideally for Schedule II-V controlled drugs Experience establishing systems used to support commercial products in a first launch environment, including inventory and supply planning software Experience leading the serialization implementation that is Drug Supply Chain Security Act (DSCSA) compliant Comprehensive understanding of pharmaceutical development, manufacturing, packaging and labeling, serialization, and distribution Knowledge of channel strategy design and implementation, including both hub and wholesaler models Working understanding of current good manufacturing practices (cGMPs) and current good distribution practices (cGDPs) Strong initiative, accountability, independence and willingness to take ownership and drive projects to completion Ability to effectively build relationships to partner both externally and internally, including with Quality, Trade and Distribution, Pharmaceutical Development, Compliance, and Program Management Capability and vision to think strategically, coupled with the drive to implement, collaborate, and contribute across disciplines Responsibilities The Executive Director of Commercial Supply Chain Strategy will be accountable for establishing the global commercial supply chain function, commercial supplier oversight, and deliverables supporting launch and on-going supply for Definium products This role will provide leadership and vision in establishing the Commercial Supply Chain function by leveraging processes, building capability, meeting commercial supply chain requirements deliverables, and driving supply chain maturity Develop and maintain end-to-end global supply chain strategy and supply network from drug substance through to finished drug product Oversee management of commercial contract manufacturers suppliers and identify opportunities for efficiencies and cost reduction Work directly with external manufacturers and packaging organizations stakeholders to establish commercial supply agreements, meet commercial supply demand, and plan for future forecast Partner with Trade and Distribution to select and oversee third party logistics providers Lead end to end value chain planning - inventory management across raw materials, drug substance, drug products and finished goods Implement and integrate serialization solution through supply and distribution network that meets most recent DSCSA compliance requirements Develop and optimize processes and systems (i.e. ERP) by working directly with commercial, pharmaceutical development, quality, and finance to ensure short and long-term manufacturing supply needs are met The starting base pay range for this position is $238,000.00 - $310,000.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location. Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including: 100% paid health benefits including Medical, Dental and Vision for you and your dependents 401(k) program with company match and vesting after the turn of the first month after your start date Flexible time off Generous parental leave and some fun fringe perks!

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