Manager, Analytical Development and Quality Control (Brisbane, CA)

Company Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease. Position The Manager, Analytical Development and Quality Control provides strategic and technical leadership for analytical CMC activities across multiple programs, with a strong emphasis on technology transfer and knowledge management. This role ensures successful transfer of analytical methods and associated knowledge to internal teams and external stakeholders, enabling consistent execution across development and manufacturing sites. The position requires deep expertise in analytical method development, validation, transfer, and lifecycle management in alignment with ICH guidelines, along with the ability to interpret data from a range of analytical techniques to support sound technical decision-making. In addition, this role is responsible for establishing and clearly communicating analytical control strategies across cross-functional teams, ensuring alignment and scientific rigor. The Manager drives robust knowledge management practices through high-quality technical writing, documentation, and data governance, including authoring and reviewing validation, transfer, and investigation reports. Strong leadership, communication, and project management skills are essential to effectively coordinate internal teams and external partners, maintain continuity of analytical knowledge, and support informed decision-making. This position is onsite at Nurix, Brisbane, CA Required Qualifications MS in Chemistry, Analytical Chemistry, or a related field with 8–10+ years of relevant experience, or PhD in a similar discipline with 5–8+ years of relevant experience. Demonstrated leadership experience managing analytical CMC activities across multiple programs. Strong expertise in analytical method development, validation, transfer, and lifecycle management in compliance with ICH guidelines. General understanding of key analytical methods (e.g., HPLC/UPLC, GC, KF, ICP-MS, IC, XRPD, PSD) with the ability to interpret data and guide technical decisions. Proven experience authoring, reviewing, and approving analytical sections of regulatory submissions (INDs, IMPDs, NDAs, and global filings). Significant experience supporting NDA submissions and interacting with regulatory agencies. Strong technical writing skills for preparation of validation reports, transfer reports, investigation reports, and regulatory documentation. Ability to effectively communicate and justify analytical control strategies within cross-functional teams (Quality, Regulatory, Process Development) and with external stakeholders. Experience overseeing external partners (e.g., CDMOs) and managing outsourced analytical activities. Strong leadership, communication, and project management skills in a cross-functional environment. Strong technical writing and authorship skills, with the ability to prepare, review, and approve analytical reports and CMC documentation to support internal decision-making and knowledge management. Fit with Nurix Culture and Values Strong team orientation; highly collaborative Solutions and results-oriented focus Hands-on approach; resourceful and open to diverse points of view Salary Range: Manager: $147,341 – 171,488 Senior Manager: $174,036 – 198,405 Application Process Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US. Note to Employment Agencies: Please do not forward any agency resumes. Nurix will not be responsible for fees related to unsolicited resumes. Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy ( https://www.nurixtx.com/privacy-policy/ ).

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