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Director, Value and Evidence

Rhythmpharmaceuticals · Boston, MA, 02116 · Hybrid · Active · $182,000–$275,000 / year · JazzHR / ApplyToJob

Job facts

FieldValue
CompanyRhythmpharmaceuticals
TitleDirector, Value and Evidence
Normalized title-
Department / team-
LocationBoston, MA, United States
Work modelHybrid / Hybrid
Employment typeFull Time
Salary$182,000–$275,000 / year
Statusactive
ATS providerJazzHR / ApplyToJob
Posted / first seen2026-05-08 / 2026-05-30
Changed / last seen2026-05-30 / 2026-06-06

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City jobsActive postings in Boston.Open
Work model jobsActive Hybrid postings.Open
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Original postingCanonical source or apply URL captured from the ATS.Open

Linked records

CompanyRhythmpharmaceuticals
Sourcea089d8d0-2598-437f-b618-c2dc9cbdd98b
ATS providerJazzHR / ApplyToJob

Description

Company Overview Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together. Opportunity Overview Rhythm seeks an experienced individual to join our Medical Affairs North America team as Director, Value & Evidence. This position will serve as a strategic bridge between clinical development, regulatory and commercial roles, responsible for generating high quality evidence to maximize the value proposition of our assets across multiple indications associated with rare neuroendocrine diseases. This role requires leading the design and execution of studies with a focus on Patient Reported Outcomes (PRO)/Clinical Outcomes Assessments (COA), real world evidence generation and health economics and value dissemination. This individual will collaborate across regional teams, delivering evidence and/or tools to optimize decision making, support access and reimbursement and inform medical and clinical research protocols. This position will report to the Head of Value & Evidence (V&E). Responsibilities and Duties Demonstrate proven methodological and analytical expertise regarding the collection, analysis, and utilization of real-world data to provide high-quality project deliverables including abstracts, posters, and manuscripts. Demonstrate proven expertise leading Health Economic and Outcomes Research (HEOR)/real world research in the forms of COA development and/or its validation, database analysis, observational research, PRO endpoint inclusion in product labeling and other types of HEOR research. Proactively propose and prepare outcomes research protocols, statistical analysis plans (SAPs), and reports. Drive longitudinal retrospective studies of existing databases to assess patient characteristics, treatment patterns, and associated clinical, economic and/or patient-reported outcomes. Lead retrospective or prospective evaluations of disease natural history and treatment patterns, including drug utilization and adherence. Drive cross-sectional surveys of patients, caregivers, health care providers/practitioners, and/or payers/health technology assessment authorities. Lead clinical-economic models and assessments exploring burden of illness and/or comparative effectiveness. Ensure findings are communicated effectively, and as appropriate in conference presentations, publications, dossiers and other means. Create robust health technology assessment (HTA) tools to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, third-party payers and other organizations that review evidence for formulary and access decision making. Ensure and drive strategic alignment with internal teams including Medical Affairs, Market Access, Regulatory, Commercial, International and Clinical Development to incorporate strategic HEOR and COA needs at every stage of development program and throughout commercial availability. Qualifications and Skills 10+ years of relevant education and experience, including time in the bio-pharmaceuticals industry, with majority of experience in PRO drug development, regulatory submissions and the commercialization process, including designing health economics and outcomes research and evidence generation independently/autonomously. Advanced degree in epidemiology, health economics, pharmaceutical sciences, or related discipline (MS, MPH, PharmD, PhD) preferred. Experience in rare diseases strongly preferred. Knowledge of the drug development & commercialization process, HTA assessment methodologies, global reimbursement, US payers and regulatory requirements. Experience in developing submissions to European-based HTA organizations. Excellent communication, collaboration and influencing skills across internal and external stakeholders. Well-organized with strong project management skills and ability to prioritize workload This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel. The expected salary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units. More about Rhythm We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.   Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. At Rhythm our core values are: We are committed to advancing scientific understanding to improve patients’ lives We are inspired to tackle tough challenges and have the courage to ask bold questions We are eager to learn and adapt We believe collaboration and ownership are foundational for our success We value the unique contribution each individual brings to furthering our mission Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law. Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.

Full job record

Job ID5542b927fc905ffdff78b13d816b9f7259e0ad3f
Org ID73fb8494-6154-4f75-bcac-7c8caae53a03
Source IDa089d8d0-2598-437f-b618-c2dc9cbdd98b
Board IDa089d8d0-2598-437f-b618-c2dc9cbdd98b
Providerjazzhr
Provider Job KeyzrDJHAOnQh
TitleDirector, Value and Evidence
Normalized Title
Statusactive
Activeyes
Location TextBoston, MA, 02116
Department
Team
Employment Typefull_time
Workplace Typehybrid
Remote Policyhybrid
CountryUnited States
RegionMA
CityBoston
Salary Rawsalary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geogr
Salary Min182,000
Salary Max275,000
Salary CurrencyUSD
Salary Periodyear
Source URLhttps://rhythmpharmaceuticals.applytojob.com/apply/zrDJHAOnQh/Director-Value-And-Evidence
Apply URLhttps://rhythmpharmaceuticals.applytojob.com/apply/zrDJHAOnQh/Director-Value-And-Evidence
First Seen At2026-05-30 05:59:39Z
Last Seen At2026-06-06 10:47:33Z
Last Checked At2026-06-06 10:47:33Z
Last Changed At2026-05-30 05:59:39Z
Inactive At
Source Posted At2026-05-08 00:00:00Z
Source Updated At
Raw Payload Uris3://job-postings-prod-raw-590183727216/raw/provider=jazzhr/board=rhythmpharmaceuticals/date=2026-06-06/2026-06-06T10-47-31-984Z-ad93454567b82c7f03c52e5b79614639e68714c57126ce76e22da7e55ac7e265.json
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    "description_html": "<span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Company Overview</span></b></span></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.</span></span></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Opportunity Overview</span></b></span></span></span></span><br><span style=\"font-size:12pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:'Times New Roman', serif;\"><span style=\"font-size:11pt;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#212221;\">Rhythm seeks an experienced individual to join our Medical Affairs North America team as Director, Value & Evidence. This position will serve as a strategic bridge between clinical development, regulatory and commercial roles, responsible for generating high quality evidence to maximize the value proposition of our assets across multiple indications associated with rare neuroendocrine diseases. This role requires leading the design and execution of studies with a focus on Patient Reported Outcomes (PRO)/Clinical Outcomes Assessments (COA), real world evidence generation and health economics and value dissemination. This individual will collaborate across regional teams, delivering evidence and/or tools to optimize decision making, support access and reimbursement and inform medical and clinical research protocols. This position will report to the Head of Value & Evidence (V&E). </span></span></span></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Responsibilities and Duties</span></b></span></span></span></span><ul><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#212221;\">Demonstrate proven methodological and analytical expertise regarding the collection, analysis, and utilization of real-world data to provide high-quality project deliverables including abstracts, posters, and manuscripts.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Demonstrate proven expertise leading Health Economic and Outcomes Research (HEOR)/real world research in the forms of COA development and/or its validation, database analysis, observational research, PRO endpoint inclusion in product labeling and other types of HEOR research.</span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Proactively propose and prepare outcomes research protocols, statistical analysis plans (SAPs), and reports.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Drive longitudinal retrospective studies of existing databases to assess patient characteristics, treatment patterns, and associated clinical, economic and/or patient-reported outcomes.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Lead retrospective or prospective evaluations of disease natural history and treatment patterns, including drug utilization and adherence.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Drive cross-sectional surveys of patients, caregivers, health care providers/practitioners, and/or payers/health technology assessment authorities.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Lead clinical-economic models and assessments exploring burden of illness and/or comparative effectiveness.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Ensure findings are communicated effectively, and as appropriate in conference presentations, publications, dossiers and other means.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Create robust health technology assessment (HTA) tools to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, third-party payers and other organizations that review evidence for formulary and access decision making.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Ensure and drive strategic alignment with internal teams including Medical Affairs, Market Access, Regulatory, Commercial, International and Clinical Development to incorporate strategic HEOR and COA needs at every stage of development program and throughout commercial availability.</span></span></span></span></span></span></li></ul><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Qualifications and Skills</span></b></span></span></span></span><ul><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">10+ years of relevant education and experience, including time in the bio-pharmaceuticals industry, with majority of experience in PRO drug development, regulatory submissions and the commercialization process, including designing health economics and outcomes research and evidence generation independently/autonomously.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Advanced degree in epidemiology, health economics, pharmaceutical sciences, or related discipline (MS, MPH, PharmD, PhD) preferred.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Experience in rare diseases strongly preferred.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#000000;\">Knowledge of the drug development & commercialization process, HTA assessment methodologies, global reimbursement, US payers and regulatory requirements.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Experience in developing submissions to European-based HTA organizations.</span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Excellent communication, collaboration and influencing skills across internal and external stakeholders.</span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Well-organized with strong project management skills and ability to prioritize workload</span></span></span></span></span></span></li></ul><br><span style=\"font-size:12pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:'Times New Roman', serif;\"><i><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#0070c0;\">This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs.</span></span></span></span></i><i><span style=\"font-size:11pt;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#0070c0;\"> <span style=\"background:#FFFFFF;\">This role may involve some travel.</span></span></span></span></i></span></span></span><br><br><span style=\"font-size:12pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:'Times New Roman', serif;\"><i><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#0070c0;\">The expected salary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.</span></span></span></span></i></span></span></span><br><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><b><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">More about Rhythm </span></span></span></i></b><br><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#000000;\">We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.</span></span></span></span></i><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">  Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. </span></span></span></i></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">At Rhythm our core values are:</span></span></span></i></span></span></span><ul><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We are committed to advancing scientific understanding to improve patients’ lives</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We are inspired to tackle tough challenges and have the courage to ask bold questions</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We are eager to learn and adapt</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We believe collaboration and ownership are foundational for our success</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We value the unique contribution each individual brings to furthering our mission</span></span></span></i></span></span></span></li></ul><div style=\"margin-left:8px;\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law. </span></span></span></i></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Headquartered in Boston, Rhythm is proud to have been named one of the </span></span></span></i><a href=\"https://www.bostonglobe.com/magazine/top-places-work/2023/\" style=\"color:#467886;text-decoration:underline;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Top Places to Work</span></span></span></i></a><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"> in Massachusetts.</span></span></span></i></span></span></span>",
    "description_text": "Company Overview\n Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.\n Opportunity Overview\n Rhythm seeks an experienced individual to join our Medical Affairs North America team as Director, Value & Evidence. This position will serve as a strategic bridge between clinical development, regulatory and commercial roles, responsible for generating high quality evidence to maximize the value proposition of our assets across multiple indications associated with rare neuroendocrine diseases. This role requires leading the design and execution of studies with a focus on Patient Reported Outcomes (PRO)/Clinical Outcomes Assessments (COA), real world evidence generation and health economics and value dissemination. This individual will collaborate across regional teams, delivering evidence and/or tools to optimize decision making, support access and reimbursement and inform medical and clinical research protocols. This position will report to the Head of Value & Evidence (V&E).\n Responsibilities and Duties Demonstrate proven methodological and analytical expertise regarding the collection, analysis, and utilization of real-world data to provide high-quality project deliverables including abstracts, posters, and manuscripts.\n Demonstrate proven expertise leading Health Economic and Outcomes Research (HEOR)/real world research in the forms of COA development and/or its validation, database analysis, observational research, PRO endpoint inclusion in product labeling and other types of HEOR research.\n Proactively propose and prepare outcomes research protocols, statistical analysis plans (SAPs), and reports.\n Drive longitudinal retrospective studies of existing databases to assess patient characteristics, treatment patterns, and associated clinical, economic and/or patient-reported outcomes.\n Lead retrospective or prospective evaluations of disease natural history and treatment patterns, including drug utilization and adherence.\n Drive cross-sectional surveys of patients, caregivers, health care providers/practitioners, and/or payers/health technology assessment authorities.\n Lead clinical-economic models and assessments exploring burden of illness and/or comparative effectiveness.\n Ensure findings are communicated effectively, and as appropriate in conference presentations, publications, dossiers and other means.\n Create robust health technology assessment (HTA) tools to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, third-party payers and other organizations that review evidence for formulary and access decision making.\n Ensure and drive strategic alignment with internal teams including Medical Affairs, Market Access, Regulatory, Commercial, International and Clinical Development to incorporate strategic HEOR and COA needs at every stage of development program and throughout commercial availability.\n Qualifications and Skills 10+ years of relevant education and experience, including time in the bio-pharmaceuticals industry, with majority of experience in PRO drug development, regulatory submissions and the commercialization process, including designing health economics and outcomes research and evidence generation independently/autonomously.\n Advanced degree in epidemiology, health economics, pharmaceutical sciences, or related discipline (MS, MPH, PharmD, PhD) preferred.\n Experience in rare diseases strongly preferred.\n Knowledge of the drug development & commercialization process, HTA assessment methodologies, global reimbursement, US payers and regulatory requirements.\n Experience in developing submissions to European-based HTA organizations.\n Excellent communication, collaboration and influencing skills across internal and external stakeholders.\n Well-organized with strong project management skills and ability to prioritize workload\n This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel.\n The expected salary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.\n More about Rhythm\n We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.   Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.\n At Rhythm our core values are: We are committed to advancing scientific understanding to improve patients’ lives\n We are inspired to tackle tough challenges and have the courage to ask bold questions\n We are eager to learn and adapt\n We believe collaboration and ownership are foundational for our success\n We value the unique contribution each individual brings to furthering our mission\n Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law.\n Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.",
    "jsonld_jobposting": {
      "url": "https://rhythmpharmaceuticals.applytojob.com/apply/zrDJHAOnQh/Director-Value-And-Evidence",
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      "title": "Director, Value and Evidence",
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      "datePosted": "2026-05-08",
      "description": "<span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Company Overview</span></b></span></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.</span></span></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Opportunity Overview</span></b></span></span></span></span><br><span style=\"font-size:12pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:'Times New Roman', serif;\"><span style=\"font-size:11pt;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#212221;\">Rhythm seeks an experienced individual to join our Medical Affairs North America team as Director, Value & Evidence. This position will serve as a strategic bridge between clinical development, regulatory and commercial roles, responsible for generating high quality evidence to maximize the value proposition of our assets across multiple indications associated with rare neuroendocrine diseases. This role requires leading the design and execution of studies with a focus on Patient Reported Outcomes (PRO)/Clinical Outcomes Assessments (COA), real world evidence generation and health economics and value dissemination. This individual will collaborate across regional teams, delivering evidence and/or tools to optimize decision making, support access and reimbursement and inform medical and clinical research protocols. This position will report to the Head of Value & Evidence (V&E). </span></span></span></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Responsibilities and Duties</span></b></span></span></span></span><ul><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#212221;\">Demonstrate proven methodological and analytical expertise regarding the collection, analysis, and utilization of real-world data to provide high-quality project deliverables including abstracts, posters, and manuscripts.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Demonstrate proven expertise leading Health Economic and Outcomes Research (HEOR)/real world research in the forms of COA development and/or its validation, database analysis, observational research, PRO endpoint inclusion in product labeling and other types of HEOR research.</span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Proactively propose and prepare outcomes research protocols, statistical analysis plans (SAPs), and reports.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Drive longitudinal retrospective studies of existing databases to assess patient characteristics, treatment patterns, and associated clinical, economic and/or patient-reported outcomes.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Lead retrospective or prospective evaluations of disease natural history and treatment patterns, including drug utilization and adherence.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Drive cross-sectional surveys of patients, caregivers, health care providers/practitioners, and/or payers/health technology assessment authorities.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Lead clinical-economic models and assessments exploring burden of illness and/or comparative effectiveness.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Ensure findings are communicated effectively, and as appropriate in conference presentations, publications, dossiers and other means.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Create robust health technology assessment (HTA) tools to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, third-party payers and other organizations that review evidence for formulary and access decision making.</span></span></span></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Ensure and drive strategic alignment with internal teams including Medical Affairs, Market Access, Regulatory, Commercial, International and Clinical Development to incorporate strategic HEOR and COA needs at every stage of development program and throughout commercial availability.</span></span></span></span></span></span></li></ul><br><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span><span style=\"font-family:Aptos, sans-serif;\"><b><span style=\"font-family:Calibri, sans-serif;\">Qualifications and Skills</span></b></span></span></span></span><ul><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">10+ years of relevant education and experience, including time in the bio-pharmaceuticals industry, with majority of experience in PRO drug development, regulatory submissions and the commercialization process, including designing health economics and outcomes research and evidence generation independently/autonomously.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Advanced degree in epidemiology, health economics, pharmaceutical sciences, or related discipline (MS, MPH, PharmD, PhD) preferred.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Experience in rare diseases strongly preferred.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#000000;\">Knowledge of the drug development & commercialization process, HTA assessment methodologies, global reimbursement, US payers and regulatory requirements.</span></span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Experience in developing submissions to European-based HTA organizations.</span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Excellent communication, collaboration and influencing skills across internal and external stakeholders.</span></span></span></span></span></li><li><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"color:#212221;\"><span style=\"line-height:normal;\"><span style=\"font-family:Aptos, sans-serif;\"><span style=\"font-family:Calibri, sans-serif;\">Well-organized with strong project management skills and ability to prioritize workload</span></span></span></span></span></span></li></ul><br><span style=\"font-size:12pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:'Times New Roman', serif;\"><i><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#0070c0;\">This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs.</span></span></span></span></i><i><span style=\"font-size:11pt;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#0070c0;\"> <span style=\"background:#FFFFFF;\">This role may involve some travel.</span></span></span></span></i></span></span></span><br><br><span style=\"font-size:12pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:'Times New Roman', serif;\"><i><span style=\"font-size:11pt;\"><span style=\"background:#FFFFFF;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#0070c0;\">The expected salary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.</span></span></span></span></i></span></span></span><br><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><b><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">More about Rhythm </span></span></span></i></b><br><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><span style=\"color:#000000;\">We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.</span></span></span></span></i><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">  Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. </span></span></span></i></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">At Rhythm our core values are:</span></span></span></i></span></span></span><ul><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We are committed to advancing scientific understanding to improve patients’ lives</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We are inspired to tackle tough challenges and have the courage to ask bold questions</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We are eager to learn and adapt</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We believe collaboration and ownership are foundational for our success</span></span></span></i></span></span></span></li><li style=\"margin-left:8px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:107%;\"><span style=\"font-family:Calibri, sans-serif;\">We value the unique contribution each individual brings to furthering our mission</span></span></span></i></span></span></span></li></ul><div style=\"margin-left:8px;\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law. </span></span></span></i></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Aptos, sans-serif;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Headquartered in Boston, Rhythm is proud to have been named one of the </span></span></span></i><a href=\"https://www.bostonglobe.com/magazine/top-places-work/2023/\" style=\"color:#467886;text-decoration:underline;\"><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Top Places to Work</span></span></span></i></a><i><span style=\"font-size:10pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"> in Massachusetts.</span></span></span></i></span></span></span>",
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