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HomeCompaniesPharmaessentiausaSenior / Principal Scientist, Immunology & Pharmacology

Senior / Principal Scientist, Immunology & Pharmacology

Pharmaessentiausa · BEDFORD, MA, 01730 · Active · JazzHR / ApplyToJob

Job facts

FieldValue
CompanyPharmaessentiausa
TitleSenior / Principal Scientist, Immunology & Pharmacology
Normalized title-
Department / team-
LocationBEDFORD, MA, United States
Work model-
Employment typeFull Time
SalaryUSD
Statusactive
ATS providerJazzHR / ApplyToJob
Posted / first seen2026-05-15 / 2026-05-30
Changed / last seen2026-05-30 / 2026-06-06

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CompanyPharmaessentiausa
Source4c0696ba-8659-4a0a-aeac-85216b08f3e7
ATS providerJazzHR / ApplyToJob

Description

Senior / Principal Scientist, Immunology & Pharmacology PharmaEssentia Innovation Research Center (PIRC) The Opportunity PharmaEssentia Innovation Research Center (PIRC) is expanding its drug discovery organization in the Greater Boston area and is seeking an experienced and highly motivated Senior or Principal Scientist with expertise in immunology, immuno-oncology, and translational pharmacology. This role will lead and execute in vitro, ex vivo, and in vivo pharmacology studies supporting target validation and advancement of early-stage therapeutic programs. The successful candidate will combine strong biological insight, technical rigor, and strategic thinking to generate data that drives discovery and preclinical development decisions. About PharmaEssentia & PIRC PharmaEssentia Corporation is a global biopharmaceutical company founded in 2003, focused on developing innovative biologic therapeutics in hematology, oncology, and immunology. With a commercial-stage product and an expanding pipeline, PharmaEssentia integrates scientific excellence with innovative technologies to address diseases with significant unmet medical need. Established in 2023, the PharmaEssentia Innovation Research Center (PIRC) is dedicated to advancing next-generation therapeutics through translational science, protein engineering, and novel therapeutic modalities. PIRC leverages deep expertise in oncology and immunology to identify and develop transformative therapeutic opportunities. Key Responsibilities Discovery & Target Validation Collaborate with internal research teams and external partners to identify, evaluate, and prioritize novel therapeutic targets. Design and execute proof-of-concept (POC) studies to validate biological hypotheses and therapeutic mechanisms. Pharmacology Strategy & Execution Develop and optimize in vitro, ex vivo, and in vivo pharmacology assays. Generate high-quality, reproducible datasets to support discovery-stage decision making and program advancement. Apply mechanistic understanding of immunology and oncology to interpret experimental outcomes. Program Leadership & Scientific Contribution Partner with project leaders to define scientific strategy, milestones, and deliverables. Contribute to advancement of discovery and preclinical programs toward IND-enabling studies. Provide scientific leadership across programs and mentor junior scientists. Cross-Functional Collaboration Work effectively within multidisciplinary teams spanning biologics discovery, translational science, bioinformatics/data science, and external CRO collaborators. Ensure timely analysis, interpretation, and communication of critical data and project updates. Scientific Communication Present clear, data-driven scientific findings to internal and external stakeholders. Maintain awareness of emerging advances in immunology, oncology, and therapeutic modalities relevant to pipeline strategy. Qualifications Education & Experience Ph.D. in Immunology, Oncology, Pharmacology, or a related discipline. Strong scientific background and hands-on experience in immunology and/or oncology drug discovery. Experience supporting discovery and preclinical-stage therapeutic programs. Approximately 6+ years of relevant industry experience. Technical Expertise Hands-on experience with human primary immune cell assays and translational pharmacology workflows. Proficiency in multi-color flow cytometry (FACS), ELISA, MSD, and related immunological assay platforms. Experience with engineered cytokines, bispecific antibodies, antibody-drug conjugates (ADCs), and/or other novel therapeutic modalities preferred. Familiarity with AI-enabled or computational approaches supporting drug discovery is highly desirable. Core Competencies Strong analytical, experimental design, and critical thinking skills. Ability to work independently while thriving in a collaborative, fast-paced research environment. Excellent written, verbal, and presentation communication skills. Why Join PIRC Opportunity to directly influence early-stage therapeutic innovation and pipeline strategy. Collaborative and science-driven research culture. Competitive compensation and benefits package, including 401(k) matching and comprehensive health coverage. Equal Employment Opportunity At PharmaEssentia Innovation Research Center (PIRC), we are committed to fostering a diverse, inclusive, and respectful workplace. We provide equal employment opportunities to all applicants and employees without regard to race, color, religion, sex, pregnancy, national origin, age, disability, marital status, sexual orientation, gender identity or expression, genetic information, veteran status, or any other protected characteristic under applicable law. PIRC does not accept unsolicited resumes from staffing agencies. Any unsolicited resumes submitted to PIRC employees or HR will become the property of PIRC without obligation or fee.   At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer. https://us.pharmaessentia.com/careers/

Full job record

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Org IDfd8f94d7-6eae-4c63-a5bc-68250f887e81
Source ID4c0696ba-8659-4a0a-aeac-85216b08f3e7
Board ID4c0696ba-8659-4a0a-aeac-85216b08f3e7
Providerjazzhr
Provider Job KeyJuUDSmZ3qD
TitleSenior / Principal Scientist, Immunology & Pharmacology
Normalized Title
Statusactive
Activeyes
Location TextBEDFORD, MA, 01730
Department
Team
Employment Typefull_time
Workplace Type
Remote Policy
CountryUnited States
RegionMA
CityBEDFORD
Salary RawUSD
Salary Min
Salary Max
Salary Currency
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Source URLhttps://pharmaessentiausa.applytojob.com/apply/JuUDSmZ3qD/Senior-Principal-Scientist-Immunology-Pharmacology
Apply URLhttps://pharmaessentiausa.applytojob.com/apply/JuUDSmZ3qD/Senior-Principal-Scientist-Immunology-Pharmacology
First Seen At2026-05-30 05:48:15Z
Last Seen At2026-06-06 20:10:56Z
Last Checked At2026-06-06 20:10:56Z
Last Changed At2026-05-30 05:48:15Z
Inactive At
Source Posted At2026-05-15 00:00:00Z
Source Updated At
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    "description_html": "<span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">Senior / Principal Scientist, Immunology & Pharmacology</span></span></b><br><i>PharmaEssentia Innovation Research Center (PIRC)</i></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">The Opportunity</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">PharmaEssentia Innovation Research Center (PIRC) is expanding its drug discovery organization in the Greater Boston area and is seeking an experienced and highly motivated Senior or Principal Scientist with expertise in immunology, immuno-oncology, and translational pharmacology.</span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">This role will lead and execute in vitro, ex vivo, and in vivo pharmacology studies supporting target validation and advancement of early-stage therapeutic programs. The successful candidate will combine strong biological insight, technical rigor, and strategic thinking to generate data that drives discovery and preclinical development decisions.</span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">About PharmaEssentia & PIRC</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">PharmaEssentia Corporation is a global biopharmaceutical company founded in 2003, focused on developing innovative biologic therapeutics in hematology, oncology, and immunology. With a commercial-stage product and an expanding pipeline, PharmaEssentia integrates scientific excellence with innovative technologies to address diseases with significant unmet medical need.</span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Established in 2023, the PharmaEssentia Innovation Research Center (PIRC) is dedicated to advancing next-generation therapeutics through translational science, protein engineering, and novel therapeutic modalities. PIRC leverages deep expertise in oncology and immunology to identify and develop transformative therapeutic opportunities.</span></span></span><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">Key Responsibilities</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Discovery & Target Validation</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Collaborate with internal research teams and external partners to identify, evaluate, and prioritize novel therapeutic targets. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Design and execute proof-of-concept (POC) studies to validate biological hypotheses and therapeutic mechanisms. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Pharmacology Strategy & Execution</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Develop and optimize in vitro, ex vivo, and in vivo pharmacology assays. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Generate high-quality, reproducible datasets to support discovery-stage decision making and program advancement. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Apply mechanistic understanding of immunology and oncology to interpret experimental outcomes. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Program Leadership & Scientific Contribution</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Partner with project leaders to define scientific strategy, milestones, and deliverables. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Contribute to advancement of discovery and preclinical programs toward IND-enabling studies. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Provide scientific leadership across programs and mentor junior scientists. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Cross-Functional Collaboration</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Work effectively within multidisciplinary teams spanning biologics discovery, translational science, bioinformatics/data science, and external CRO collaborators. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Ensure timely analysis, interpretation, and communication of critical data and project updates. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Scientific Communication</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Present clear, data-driven scientific findings to internal and external stakeholders. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Maintain awareness of emerging advances in immunology, oncology, and therapeutic modalities relevant to pipeline strategy. </span></span></span></span></li></ul><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">Qualifications</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Education & Experience</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Ph.D. in Immunology, Oncology, Pharmacology, or a related discipline. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Strong scientific background and hands-on experience in immunology and/or oncology drug discovery. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Experience supporting discovery and preclinical-stage therapeutic programs. </span></span></span></span></li></ul><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Approximately 6+ years of relevant industry experience. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Technical Expertise</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Hands-on experience with human primary immune cell assays and translational pharmacology workflows. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Proficiency in multi-color flow cytometry (FACS), ELISA, MSD, and related immunological assay platforms. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Experience with engineered cytokines, bispecific antibodies, antibody-drug conjugates (ADCs),<b> </b>and/or other novel therapeutic modalities preferred. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Familiarity with AI-enabled or computational approaches supporting drug discovery is highly desirable. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Core Competencies</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Strong analytical, experimental design, and critical thinking skills. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Ability to work independently while thriving in a collaborative, fast-paced research environment. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Excellent written, verbal, and presentation communication skills. </span></span></span></span></li></ul><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Why Join PIRC</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Opportunity to directly influence early-stage therapeutic innovation and pipeline strategy. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Collaborative and science-driven research culture. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Competitive compensation and benefits package, including 401(k) matching and comprehensive health coverage. </span></span></span></span></li></ul><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Equal Employment Opportunity</b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><i>At PharmaEssentia Innovation Research Center (PIRC), we are committed to fostering a diverse, inclusive, and respectful workplace. We provide equal employment opportunities to all applicants and employees without regard to race, color, religion, sex, pregnancy, national origin, age, disability, marital status, sexual orientation, gender identity or expression, genetic information, veteran status, or any other protected characteristic under applicable law.</i></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><i>PIRC does not accept unsolicited resumes from staffing agencies. Any unsolicited resumes submitted to PIRC employees or HR will become the property of PIRC without obligation or fee.</i></span></span></span><br> <p>At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.</p>\n\n<p><a href=\\\"https://us.pharmaessentia.com/careers/\\\">https://us.pharmaessentia.com/careers/</a></p>",
    "description_text": "Senior / Principal Scientist, Immunology & Pharmacology\n PharmaEssentia Innovation Research Center (PIRC)\n The Opportunity\n PharmaEssentia Innovation Research Center (PIRC) is expanding its drug discovery organization in the Greater Boston area and is seeking an experienced and highly motivated Senior or Principal Scientist with expertise in immunology, immuno-oncology, and translational pharmacology.\n This role will lead and execute in vitro, ex vivo, and in vivo pharmacology studies supporting target validation and advancement of early-stage therapeutic programs. The successful candidate will combine strong biological insight, technical rigor, and strategic thinking to generate data that drives discovery and preclinical development decisions.\n About PharmaEssentia & PIRC\n PharmaEssentia Corporation is a global biopharmaceutical company founded in 2003, focused on developing innovative biologic therapeutics in hematology, oncology, and immunology. With a commercial-stage product and an expanding pipeline, PharmaEssentia integrates scientific excellence with innovative technologies to address diseases with significant unmet medical need.\n Established in 2023, the PharmaEssentia Innovation Research Center (PIRC) is dedicated to advancing next-generation therapeutics through translational science, protein engineering, and novel therapeutic modalities. PIRC leverages deep expertise in oncology and immunology to identify and develop transformative therapeutic opportunities.\n Key Responsibilities\n Discovery & Target Validation Collaborate with internal research teams and external partners to identify, evaluate, and prioritize novel therapeutic targets.\n Design and execute proof-of-concept (POC) studies to validate biological hypotheses and therapeutic mechanisms.\n Pharmacology Strategy & Execution Develop and optimize in vitro, ex vivo, and in vivo pharmacology assays.\n Generate high-quality, reproducible datasets to support discovery-stage decision making and program advancement.\n Apply mechanistic understanding of immunology and oncology to interpret experimental outcomes.\n Program Leadership & Scientific Contribution Partner with project leaders to define scientific strategy, milestones, and deliverables.\n Contribute to advancement of discovery and preclinical programs toward IND-enabling studies.\n Provide scientific leadership across programs and mentor junior scientists.\n Cross-Functional Collaboration Work effectively within multidisciplinary teams spanning biologics discovery, translational science, bioinformatics/data science, and external CRO collaborators.\n Ensure timely analysis, interpretation, and communication of critical data and project updates.\n Scientific Communication Present clear, data-driven scientific findings to internal and external stakeholders.\n Maintain awareness of emerging advances in immunology, oncology, and therapeutic modalities relevant to pipeline strategy.\n Qualifications\n Education & Experience Ph.D. in Immunology, Oncology, Pharmacology, or a related discipline.\n Strong scientific background and hands-on experience in immunology and/or oncology drug discovery.\n Experience supporting discovery and preclinical-stage therapeutic programs.\n Approximately 6+ years of relevant industry experience.\n Technical Expertise Hands-on experience with human primary immune cell assays and translational pharmacology workflows.\n Proficiency in multi-color flow cytometry (FACS), ELISA, MSD, and related immunological assay platforms.\n Experience with engineered cytokines, bispecific antibodies, antibody-drug conjugates (ADCs), and/or other novel therapeutic modalities preferred.\n Familiarity with AI-enabled or computational approaches supporting drug discovery is highly desirable.\n Core Competencies Strong analytical, experimental design, and critical thinking skills.\n Ability to work independently while thriving in a collaborative, fast-paced research environment.\n Excellent written, verbal, and presentation communication skills.\n Why Join PIRC Opportunity to directly influence early-stage therapeutic innovation and pipeline strategy.\n Collaborative and science-driven research culture.\n Competitive compensation and benefits package, including 401(k) matching and comprehensive health coverage.\n Equal Employment Opportunity\n At PharmaEssentia Innovation Research Center (PIRC), we are committed to fostering a diverse, inclusive, and respectful workplace. We provide equal employment opportunities to all applicants and employees without regard to race, color, religion, sex, pregnancy, national origin, age, disability, marital status, sexual orientation, gender identity or expression, genetic information, veteran status, or any other protected characteristic under applicable law.\n PIRC does not accept unsolicited resumes from staffing agencies. Any unsolicited resumes submitted to PIRC employees or HR will become the property of PIRC without obligation or fee.\n  At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.\n https://us.pharmaessentia.com/careers/",
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      "description": "<span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">Senior / Principal Scientist, Immunology & Pharmacology</span></span></b><br><i>PharmaEssentia Innovation Research Center (PIRC)</i></span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">The Opportunity</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">PharmaEssentia Innovation Research Center (PIRC) is expanding its drug discovery organization in the Greater Boston area and is seeking an experienced and highly motivated Senior or Principal Scientist with expertise in immunology, immuno-oncology, and translational pharmacology.</span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">This role will lead and execute in vitro, ex vivo, and in vivo pharmacology studies supporting target validation and advancement of early-stage therapeutic programs. The successful candidate will combine strong biological insight, technical rigor, and strategic thinking to generate data that drives discovery and preclinical development decisions.</span></span></span><br><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">About PharmaEssentia & PIRC</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">PharmaEssentia Corporation is a global biopharmaceutical company founded in 2003, focused on developing innovative biologic therapeutics in hematology, oncology, and immunology. With a commercial-stage product and an expanding pipeline, PharmaEssentia integrates scientific excellence with innovative technologies to address diseases with significant unmet medical need.</span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\">Established in 2023, the PharmaEssentia Innovation Research Center (PIRC) is dedicated to advancing next-generation therapeutics through translational science, protein engineering, and novel therapeutic modalities. PIRC leverages deep expertise in oncology and immunology to identify and develop transformative therapeutic opportunities.</span></span></span><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">Key Responsibilities</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Discovery & Target Validation</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Collaborate with internal research teams and external partners to identify, evaluate, and prioritize novel therapeutic targets. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Design and execute proof-of-concept (POC) studies to validate biological hypotheses and therapeutic mechanisms. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Pharmacology Strategy & Execution</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Develop and optimize in vitro, ex vivo, and in vivo pharmacology assays. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Generate high-quality, reproducible datasets to support discovery-stage decision making and program advancement. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Apply mechanistic understanding of immunology and oncology to interpret experimental outcomes. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Program Leadership & Scientific Contribution</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Partner with project leaders to define scientific strategy, milestones, and deliverables. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Contribute to advancement of discovery and preclinical programs toward IND-enabling studies. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Provide scientific leadership across programs and mentor junior scientists. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Cross-Functional Collaboration</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Work effectively within multidisciplinary teams spanning biologics discovery, translational science, bioinformatics/data science, and external CRO collaborators. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Ensure timely analysis, interpretation, and communication of critical data and project updates. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Scientific Communication</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Present clear, data-driven scientific findings to internal and external stakeholders. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Maintain awareness of emerging advances in immunology, oncology, and therapeutic modalities relevant to pipeline strategy. </span></span></span></span></li></ul><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b><span style=\"font-size:12pt;\"><span style=\"line-height:115%;\">Qualifications</span></span></b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Education & Experience</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Ph.D. in Immunology, Oncology, Pharmacology, or a related discipline. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Strong scientific background and hands-on experience in immunology and/or oncology drug discovery. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Experience supporting discovery and preclinical-stage therapeutic programs. </span></span></span></span></li></ul><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Approximately 6+ years of relevant industry experience. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Technical Expertise</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Hands-on experience with human primary immune cell assays and translational pharmacology workflows. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Proficiency in multi-color flow cytometry (FACS), ELISA, MSD, and related immunological assay platforms. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Experience with engineered cytokines, bispecific antibodies, antibody-drug conjugates (ADCs),<b> </b>and/or other novel therapeutic modalities preferred. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Familiarity with AI-enabled or computational approaches supporting drug discovery is highly desirable. </span></span></span></span></li></ul><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Core Competencies</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Strong analytical, experimental design, and critical thinking skills. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Ability to work independently while thriving in a collaborative, fast-paced research environment. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Excellent written, verbal, and presentation communication skills. </span></span></span></span></li></ul><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Why Join PIRC</b></span></span></span><ul style=\"margin-bottom:11px;\"><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Opportunity to directly influence early-stage therapeutic innovation and pipeline strategy. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Collaborative and science-driven research culture. </span></span></span></span></li><li style=\"margin-bottom:11px;\"><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span><span style=\"font-family:Calibri, sans-serif;\">Competitive compensation and benefits package, including 401(k) matching and comprehensive health coverage. </span></span></span></span></li></ul><div align=\"center\" style=\"text-align:center;margin-bottom:11px;\"><hr align=\"center\" size=\"2\" width=\"100%\"></div><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><b>Equal Employment Opportunity</b></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><i>At PharmaEssentia Innovation Research Center (PIRC), we are committed to fostering a diverse, inclusive, and respectful workplace. We provide equal employment opportunities to all applicants and employees without regard to race, color, religion, sex, pregnancy, national origin, age, disability, marital status, sexual orientation, gender identity or expression, genetic information, veteran status, or any other protected characteristic under applicable law.</i></span></span></span><br><span style=\"font-size:11pt;\"><span style=\"line-height:115%;\"><span style=\"font-family:Calibri, sans-serif;\"><i>PIRC does not accept unsolicited resumes from staffing agencies. Any unsolicited resumes submitted to PIRC employees or HR will become the property of PIRC without obligation or fee.</i></span></span></span><br> <p>At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.</p>\n\n<p><a href=\\\"https://us.pharmaessentia.com/careers/\\\">https://us.pharmaessentia.com/careers/</a></p>",
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