Director, Medical Affairs, Lung

About Summit: Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence. Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including: Non-small Cell Lung Cancer (NSCLC) HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI. HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC. HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC. Colorectal Cancer (CRC) HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy. Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland. Overview The Director, Medical Affairs, Lung, supports the medical strategy and tactical execution for the launch of therapies in lung-related indications. This role focuses on developing and implementing disease and product education, medical communications, and engaging stakeholders to ensure meeting educational needs and gather scientific and medical insights to be reported across the organization. The Director works closely with cross-functional teams and external partners, contributing to regulatory alignment and commercialization efforts. Key Responsibilities Work under the guidance of senior medical affairs leadership, providing operational and scientific support across projects. Focus on executing plans and maintaining high-quality standards in medical affairs activities. Key contributor to the medical efforts supporting the launch of ivonescimab in lung-related indications. Execute and continuously amend the comprehensive launch plan, including pre-launch activities, stakeholder engagement, and post-launch support. Develop and implement pre-launch disease and product education programs for healthcare professionals, patients, and other stakeholders. Create training materials, presentations, and educational content to ensure a thorough understanding of ivonescimab and its therapeutic benefits. Work closely with regulatory, legal, and compliance stakeholders to ensure medical activities relating to commercialization of ivonescimab are compliant with all relevant laws, regulations, and company policies, including review of medical and commercial material. Build and maintain relationships with key opinion leaders, healthcare professionals, and other stakeholders to support the successful launch and appropriate adoption of ivonescimab. Analyze and interpret clinical data to provide medical insights and support decision-making processes. Collaborate with cross-functional teams, including marketing, sales, and market access, to ensure the medical strategy supports commercial objectives. Provide accurate and up-to-date medical information to internal and external stakeholders, including development and delivery of disease and product education scientific data to healthcare professionals, patients, and stakeholders. Requirements: Education Advanced scientific degree (MD, PharmD, PhD) required. Experience Minimum of 6 years progressive Medical Affairs experience with at least 2 years in an in-house position. Clinical experience and/or drug launch experience in lung cancer is highly preferred. Proven track record in leading medical strategies and supporting launch and on market oncology therapies. Experience in a biotech or fast paced, evolving environment preferred. Skills & Abilities Strong analytical and problem-solving skills with the ability to interpret complex scientific data. Excellent communication and collaboration skills. With the ability to demonstrate prior success in working with commercial departments. Ability to work independently and as part of a team. Detail-oriented with strong organizational skills. Demonstrated ability to interact with senior management, academic experts, and patient advocates appropriately, with confidence and ease. Domestic and international travel required, expected to be 20-30% of the time and as needed. Proficient user of standard MS Office suite (e.g., Word, Excel), experience using electronic document management systems, and document review tools. Must be able to effectively multi-task and manage time-sensitive and highly confidential documents. Work in a fast-paced, demanding, and collaborative environment. This is the pay for this position Pay Transparency $239,000 — $289,000 USD Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation. Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at [email protected] to obtain prior written authorization before referring any candidates to Summit. Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

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