IT Systems Engineer

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives. Position Summary: As an IT Systems Engineer at Orca Bio, reporting into our IT Manager, you will take on the responsibility of building, supporting, maintaining, and optimizing the IT infrastructure on premise and in the cloud. To thrive, you must possess a strong technical foundation across systems and cloud platforms, along with a proactive, problem-solving mindset. You should be comfortable automating routine tasks, and driving improvements through scalable, secure, and reliable solutions. Excellent communication and collaboration skills are essential, as you’ll be working cross-functionally to support fast-paced research, development, and production environments. A strong sense of ownership, adaptability, and a passion for continuous learning will set you apart. Location: This is an in-office position, based at our production facility in Sacramento. The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations. Who we are We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them. We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility. We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo. We maintain a start-up culture of camaraderie and leadership by example, regardless of title. We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers. Notice to staffing firms Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment. Key Responsibilities Plan, deploy, and configure servers, storage systems, networks, cloud applications, and other IT infrastructure components to meet organizational needs. Ensure systems are running optimally by conducting maintenance, applying updates and patches, and monitoring system performance and availability. Diagnose and resolve hardware, software, and network issues. Provide Tier 2/3 technical support to end-users and IT Helpdesk staff. Implement and maintain security protocols, including firewalls, antivirus solutions, and intrusion detection systems. Perform regular security audits and vulnerability assessments. Develop scripts and tools to automate tasks, improve system performance, and enhance operational efficiency. Maintain detailed documentation of system configurations, changes, and processes. Generate reports on system performance, usage, and incidents. Work closely with cross-functional teams to align IT systems with business goals, support projects, and ensure seamless integration of new technologies. Required Experience Bachelor’s Degree in Computer Science, Management Information Systems, or equivalent experience. A minimum of 3+ years of IT Systems Administration experience. Experience with corporate data/knowledge management. Preferred Experience Experience working in biotech, healthcare or another highly regulated environment. Advanced knowledge of Microsoft 365 including Entra ID, Exchange Online, Intune, SharePoint Online. Mobile device management (MDM) experience. Working knowledge of administering on premise virtual environments. Experience with enterprise backups, replication, and disaster recovery. Experience with configuring, modifying, and troubleshooting Okta Application Integrations. Working knowledge of infrastructure automation and management. Experience with setup, administration, and maintenance of NAS/SAN storage arrays. Experience with managing enterprise firewalls, networking equipment, and wireless access points spanning multiple physical locations, subnets, and VLANs. General knowledge of programming principles and comfort with using common scripting languages such as Python, and PowerShell. General understanding of system integration approaches and requirements.

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