Senior Director, Clinical Pharmacology

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    "url": "https://recruiting.paylocity.com/recruiting/jobs/Details/4035637/Bridge-Bio-Oncology-Therapeutics/Senior-Director-Clinical-Pharmacology",
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    "html_title": "Bridge Bio Oncology Therapeutics - Senior Director, Clinical Pharmacology",
    "description_html": "<p><strong>BridgeBio Oncology Therapeutics (“BBOT”) </strong>is a clinical-stage biopharmaceutical company advancing a next-generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies. BBOT has the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors.&nbsp;</p><p>For more information visit BBOTx.com</p><p>&nbsp;</p><p><strong>We are seeking an experienced and visionary Senior/Executive Director, Clinical Pharmacology to lead clinical pharmacology efforts to support multiple oncology programs.</strong></p><p><br></p><p><strong>Responsibilities</strong></p><ul><li>Lead the clinical pharmacology strategy for multiple oncology programs, ensuring alignment with regulatory requirements and scientific standards.</li><li>Design and oversee clinical pharmacology studies to support multiple oncology program clinical development.</li><li>Collaborate with cross-functional teams, including clinical operations, biostatistics, and regulatory affairs, to drive the advancement of drug development programs.</li><li>Drive application of model-informed drug development (MIDD) approaches, including population PK/PD and exposure–response analyses.</li><li>Author relevant sections/modules of regulatory documents (including INDs, IBs, CTAs, IMPDs, NDAs, briefing packages, or other regulatory dossier) and serve as subject matter expert in regulatory interactions with FDA and other global health authorities.&nbsp;</li><li>Stay abreast of industry trends and advancements in clinical pharmacology and oncology, contributing to the scientific community through presentations and publications.</li></ul>",
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    "requirements_html": "<p><strong>Education, Experience, and Skills Requirements</strong></p><ul><li>Ph.D. or equivalent in pharmacokinetics (PK)/pharmacodynamics (PD), Pharmacology, Chemistry, or a related field.&nbsp;</li><li>Minimum of 10 years (SD) or 15 years (ED) of experience in clinical pharmacology, particularly with small molecule modality within the oncology therapeutic area.</li><li>Proven track record of successfully managing clinical pharmacology studies and developing regulatory submissions.</li><li>Strong understanding of oncology drug development processes and regulatory guidelines.&nbsp;</li><li>Quantitative pharmacology skillset preferred, e.g. PBPK, PK/PD modeling, population PK, and exposure-response analyses.</li><li>Excellent communication and interpersonal skills, with the ability to work collaboratively in a team environment.</li></ul><p>&nbsp;</p><p><strong>Compensation</strong></p><p>BBOT considers a variety of factors when determining base compensation, including experience, skills, education, qualifications, and geographic location. Actual compensation will vary, and it is not typical to be hired at or near the top of the range for the role. &nbsp;</p><p><br></p><p>Base compensation is part of a robust total rewards offering at BBOT. Additional total rewards elements include annual bonus, stock-based long-term incentives, medical, dental, and vision benefits, retirement, wellness stipend, and flexible time off.&nbsp;</p>",
    "requirements_text": "Education, Experience, and Skills Requirements\n Ph.D. or equivalent in pharmacokinetics (PK)/pharmacodynamics (PD), Pharmacology, Chemistry, or a related field.\n Minimum of 10 years (SD) or 15 years (ED) of experience in clinical pharmacology, particularly with small molecule modality within the oncology therapeutic area.\n Proven track record of successfully managing clinical pharmacology studies and developing regulatory submissions.\n Strong understanding of oncology drug development processes and regulatory guidelines.\n Quantitative pharmacology skillset preferred, e.g. PBPK, PK/PD modeling, population PK, and exposure-response analyses.\n Excellent communication and interpersonal skills, with the ability to work collaboratively in a team environment.\n Compensation\n BBOT considers a variety of factors when determining base compensation, including experience, skills, education, qualifications, and geographic location. Actual compensation will vary, and it is not typical to be hired at or near the top of the range for the role.\n Base compensation is part of a robust total rewards offering at BBOT. Additional total rewards elements include annual bonus, stock-based long-term incentives, medical, dental, and vision benefits, retirement, wellness stipend, and flexible time off."
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    "PublishedDate": "2026-06-05T10:48:42-05:00",
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