Associate Scientist II (Contract), Drug Product Analytics

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: Vaxcyte is looking for an energetic and talented individual to join our Drug Product Development team. The candidate must have knowledge of and practical experience in analyzing and characterizing biomolecules (proteins, polysaccharide conjugates, vaccines) using a variety of methods, including immunoassays, chromatography, spectrophotometric techniques, light scattering, and particle sizing. Experience in analyzing vaccine and adjuvant-containing formulations is a plus. In addition, Vaxcyte is looking for an experienced and flexible individual who would be comfortable working on multiple projects at once, with fluid prioritization to enable aggressive timelines. This position is for a lab-based scientific role and requires excellent scientific judgement, independence, rigor, and thorough record-keeping. Essential Functions: Routine and non-routine analysis of internal release, development, and stability samples and reporting of data using multiple analytical techniques across the Drug Product working groups. Executing non-GxP stability study analysis for thermal, freeze/thaw, and agitation as well as container closure system evaluation for both Drug Substance and adjuvanted vaccine Drug Product materials. Support the Vaxcyte PCV products, external analytical, and manufacturing CMOs to enable tech transfer and implementation of processes and analytical methods. This position is for a scientific role, which is predominantly lab-based, requiring excellent scientific judgement, independence, rigor, and thorough record-keeping. Requirements: BS degree in Chemistry, Biochemistry, or related field with minimum 2 years of industry experience, or MS degree with minimum 1 years of industry experience. The candidate will preferably have established practical experience in the analytical characterization of large biomolecular Drug Products in pre-filled syringes and vials. Experience executing bioanalytical components of stability studies and release tests. Experience in plate-based assays, immunoassay/ELISA, chromatography methods, spectrometric, and biophysical methodologies is preferred Experience in authoring analytical technical documents, including method protocols, SOPs, and reports, as well as experience recording and templating electronic laboratory notebooks (eLN). The candidate should have high degrees of both flexibility and organizational skills as well as an eagerness and ability to learn, to effectively navigate Vaxcyte’s multiple projects and timelines. Strong interpersonal skills; ability to communicate effectively both verbally and in written formats are necessary to collaborate effectively with the rest of the Formulation and Drug Product Development team, as well as train other analysts and team members. Detail-oriented, rigorous, and excellent skills in record keeping. Reports to: Senior Manager, Drug Product Location: San Carlos, CA Work Arrangement: Onsite (minimum of 4 days per week). Expected Contract Length: 12months Hourly Range: $51/hr. - $56/hr. We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

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