Principal Scientist/Director, Translational Pharmacology

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      "content": "<div>\n<div>\n\n<li><span data-contrast=\"auto\">Lead the design, execution, and interpretation of preclinical pharmacology studies supporting drug discovery and development programs&nbsp;</span> </li>\n<li><span data-contrast=\"auto\">Develop and apply quantitative PK/PD models, integrating pharmacokinetics, pharmacodynamics, and chemical kinetics to guide compound optimization and dosing strategies </span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">&nbsp;</span></li>\n<li><span data-contrast=\"auto\">Design and oversee in vivo studies, including selection and development of appropriate animal models&nbsp;</span></li>\n<li><span data-contrast=\"auto\">Drive rigorous data analysis, including statistical evaluation and modeling to inform decision-making</span></li>\n<li><span data-contrast=\"auto\">Translate preclinical findings into clinically relevant hypotheses and development strategies&nbsp;</span></li>\n<li><span data-contrast=\"auto\">Collaborate closely with teams to optimize drug candidates and delivery systems&nbsp;</span> </li>\n<li><span data-contrast=\"auto\">Contribute to regulatory documentation and strategy (IND-enabling studies, study reports, etc.) </span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">&nbsp;</span></li>\n<li><span data-contrast=\"auto\">Build and manage relationships with CROs and external collaborators </span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">&nbsp;</span></li>\n\n</div>\n</div>"
    },
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      "text": "Qualifications",
      "content": "<div>\n<div>\n<div>\n\n<li><span data-contrast=\"auto\">PhD, MD, or equivalent in pharmacology, biomedical sciences, or related field&nbsp;</span> </li>\n<li><span data-contrast=\"auto\">Significant experience</span><span data-contrast=\"auto\">&nbsp;in preclinical pharmacology within biotech or pharmaceutical settings&nbsp;</span> </li>\n<li><span data-contrast=\"auto\">Experience in choosing appropriate animal models</span> </li>\n<li><span data-contrast=\"auto\">Deep expertise in PK/PD modeling, with strong grounding in chemical kinetics and quantitative biology&nbsp;</span> </li>\n<li><span data-contrast=\"auto\">Proven experience designing studies to evaluate drug combinations and synergy, including application of factorial experimental design Demonstrated experience designing and interpreting in vivo pharmacology studies&nbsp;</span> </li>\n<li><span data-contrast=\"auto\">Experience in advancing preclinical candidates through IND-enabling studies and contributing meaningfully to IND submissions </span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">&nbsp;</span></li>\n<li><span data-contrast=\"auto\">Strong statistical and data analysis skills </span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">&nbsp;</span></li>\n<li><span data-contrast=\"auto\">Experience in metabolic diseases, particularly obesity and/or diabetes, strongly preferred </span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">&nbsp;</span></li>\n\n</div>\n</div>\n</div>"
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