Associate Scientist II (Contract), Analytical Development for Characterization

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: We are seeking a highly skilled and motivated Associate Scientist II (Contract) to join our Analytical Development team to support the characterization of drug substances, protein intermediates, and drug products using LC-MS and complementary analytical techniques The ideal candidate would be central to implementing mass spectrometry-based workflows, interpreting complex data, and collaborating cross-functionally to advance our vaccine programs. Essential Functions: Prepare samples and perform analyses per SOPs, including detailed data interpretation. Independently execute analytical assignments with accuracy and efficiency. Implement LC-MS workflows for proteins, conjugates, and other in-process molecules. Operate, maintain, and troubleshoot Orbitrap, qTOF, and triple quadrupole mass spectrometers. Conduct rigorous data analysis, interpret results, and present findings in team meetings. Partner cross-functionally to develop analytical strategies and support their needs. Maintain accurate documentation in an electronic lab notebook system. Requirements: BS in Chemistry, Analytical Chemistry, Biochemistry, or a related discipline, with minimum 2 years of relevant industry experience. MS without experience; or equivalent work experience. Hands-on experience utilizing mass spectrometry platforms, including hybrid Orbitraps, qTOFs, and triple quadrupoles. Familiar with peptide mapping, and intact protein analysis workflows. Excellent organizational skills, attention to detail, and documentation expertise. Strong scientific curiosity and problem-solving abilities. Effective communication and collaboration within cross-functional environments. Ability to rapidly learn analytical workflows and technologies. Experience using electronic lab notebook (ELN) systems is a plus Scientific creativity and curiosity for applying new technologies to complex analytical challenges. Reports to: Scientist II, Analytical Development Location: San Carlos, CA Expected Contract Length: 12 months Hourly Range: $51/hr. - $56/hr. We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

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