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Technical Program Manager (Sr. Mgr or Assoc. Director)

Structuretx · South San Francisco, California, 94080, United States · Hybrid · Active · $147,000–$190,000 / year · BambooHR

Job facts

FieldValue
CompanyStructuretx
TitleTechnical Program Manager (Sr. Mgr or Assoc. Director)
Normalized title-
Department / team706- IT
LocationSouth San Francisco, United States
Work modelHybrid / Hybrid
Employment typeFTE
Salary$147,000–$190,000 / year
Statusactive
ATS providerBambooHR
Posted / first seen2026-04-21 / 2026-05-30
Changed / last seen2026-05-30 / 2026-06-06

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PageWhat it containsOpen
Company jobsActive postings from Structuretx.Open
Company breakdownsRole, location, ATS, and work model facets for this company.Open
ATS provider jobsActive postings observed through BambooHR.Open
Provider filtered searchThe same provider as a filtered job collection.Open
City jobsActive postings in South San Francisco.Open
Department jobsActive postings in 706- IT.Open
Work model jobsActive Hybrid postings.Open
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Original postingCanonical source or apply URL captured from the ATS.Open

Linked records

CompanyStructuretx
Source38c0856d-8c35-49b6-a5cb-562c34852a21
ATS providerBambooHR

Description

About Us: Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions. Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location. Reporting directly or operationally into the VP, Information Technology, the role supports the broader coordination of efforts across teams to ensure impactful contributions to AI integration Position Summary: Structure Therapeutics is seeking a Sr. Technical Project / Program Manager to lead a portfolio of high-impact IT initiatives spanning R&D, G&A, and AI/Infrastructure platforms. This role is critical to enabling scientific innovation and enterprise scale by delivering complex, cross-functional programs with precision, transparency, and speed. Operating at the level expected in leading biotech organizations, this individual will drive end-to-end program execution, establish strong delivery governance, and ensure alignment between scientific, corporate, and technology priorities. This role requires a balance of deep program management discipline, technical fluency, and AI-forward thinking, with a strong focus on execution excellence and executive communication. Job Responsibilities: Program & Project Leadership Lead end-to-end delivery of complex IT programs across: R&D systems (Clinical, Discovery, Preclinical) G&A systems (Finance, HR, Legal, collaboration tools) AI/ML and infrastructure platforms Drive program planning, execution, and delivery across the full Software Development Lifecycle (SDLC) Manage multiple concurrent initiatives with clear prioritization, resource alignment, and delivery accountability Ensure delivery within scope, timeline, budget, and quality expectations Delivery Methodology & Execution Excellence Apply strong expertise in Agile, Waterfall, and hybrid delivery models , selecting the right approach based on program needs Establish structured project plans, milestones, and dependencies across technical and business teams Proactively manage risks, issues, and interdependencies with a solutions-oriented mindset Drive continuous improvement in delivery frameworks, tools, and operational rigor Cross-Functional IT & Business Partnership Work closely with IT functions including Security, Infrastructure, Applications, Data/AI, and Enterprise Systems Partner with business stakeholders across R&D and G&A to define requirements, align priorities, and drive adoption Serve as the connective layer between engineering, architecture, and business teams to ensure cohesive execution Coordinate internal teams and external vendors/partners Executive Reporting & Governance Own program governance, including steering committees, status reporting, and executive updates Deliver clear, concise, and data-driven reporting on program health, risks, and outcomes Translate complex technical initiatives into business-relevant insights for senior leadership Drive decision-making through structured communication and escalation management AI & Digital Enablement Lead and support initiatives involving AI/ML platforms, data infrastructure, and automation Demonstrate AI literacy , leveraging modern AI tools to improve productivity and delivery outcomes Partner with data and engineering teams to enable scalable, production-ready AI solutions PMO & Operational Leadership Contribute to building and scaling IT PMO capabilities , standards, and best practices Champion consistency in project execution, documentation, and reporting Mentor junior team members and promote a culture of accountability and continuous improvement Qualifications: Experience 7+ years of experience in  technical project/program management , preferably within biotech, pharma, or regulated environments Proven success delivering complex, cross-functional IT programs supporting R&D and enterprise functions Experience working in environments comparable to other biopharma Strong track record of managing enterprise-scale initiatives and executive stakeholders Technical & Delivery Expertise Strong understanding of: Software Development Lifecycle (SDLC) Agile, Waterfall, and hybrid delivery models Cloud infrastructure (AWS/Azure/GCP) Data platforms and AI/ML ecosystems Enterprise applications (Finance, HR, collaboration tools) Familiarity with GxP, validation, and compliance requirements is a plus. Leadership & Communication Exceptional skills in project management, prioritization, and execution discipline Strong experience with executive reporting and stakeholder communication Ability to influence without authority and drive alignment across diverse teams High degree of ownership, accountability, and attention to detail AI & Modern Tooling Demonstrated AI literacy , including practical use of AI tools to enhance productivity, reporting, or delivery workflows Interest in applying emerging technologies to improve IT and business outcomes Education & Certifications Bachelor’s degree in Computer Science, Engineering, or related field (Master’s preferred) PMP, PgMP, Scrum, or equivalent certification preferred Success Measures Consistent delivery of programs on time, within scope, and aligned to business outcomes High-quality executive visibility and reporting across IT initiatives Strong stakeholder satisfaction across R&D, G&A, and IT leadership Improved delivery maturity, standardization, and PMO effectiveness Successful enablement and adoption of AI and digital initiatives Travel Required:  Occasional travel may be required based on business needs. Structure Therapeutics Inc. is an Equal-Opportunity Employer. Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $147,000 - $190,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience. At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown. Notice to Recruiters/Staffing Agencies Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees. We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file. Structure Therapeutics’ receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees. Fraud Alert To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at  BambooHR . Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.

Full job record

Job ID13b5311a710a49a09e7bf947a2245334483d6971
Org IDb5f128c7-6a59-48ec-b4a1-123352a40cd1
Source ID38c0856d-8c35-49b6-a5cb-562c34852a21
Board ID38c0856d-8c35-49b6-a5cb-562c34852a21
Providerbamboohr
Provider Job Key428
TitleTechnical Program Manager (Sr. Mgr or Assoc. Director)
Normalized Title
Statusactive
Activeyes
Location TextSouth San Francisco, California, 94080, United States
Department706- IT
Team
Employment TypeFTE
Workplace Typehybrid
Remote Policyhybrid
CountryUnited States
Region
CitySouth San Francisco
Salary Rawbase pay range is $147,000 - $190,000. The exact base pay offered for this role will depend on various factors, includ
Salary Min147,000
Salary Max190,000
Salary CurrencyUSD
Salary Periodyear
Source URLhttps://structuretx.bamboohr.com/careers/428
Apply URLhttps://structuretx.bamboohr.com/careers/428
First Seen At2026-05-30 05:46:19Z
Last Seen At2026-06-06 10:25:15Z
Last Checked At2026-06-06 10:25:15Z
Last Changed At2026-05-30 05:46:19Z
Inactive At
Source Posted At2026-04-21 00:00:00Z
Source Updated At
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    "description": "<p><span style=\"font-weight: bold\">About Us:</span> </p>\n<p><br></p>\n<p>Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions. </p>\n<p><br></p>\n<p>Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location. Reporting directly or operationally into the VP, Information Technology, the role supports the broader coordination of efforts across teams to ensure impactful contributions to AI integration </p>\n<p> </p>\n<p><span style=\"font-weight: bold\">Position Summary:</span></p>\n<p><br></p>\n<p>Structure Therapeutics is seeking a Sr. Technical Project / Program Manager to lead a portfolio of high-impact IT initiatives spanning R&amp;D, G&amp;A, and AI/Infrastructure platforms. This role is critical to enabling scientific innovation and enterprise scale by delivering complex, cross-functional programs with precision, transparency, and speed.<br>Operating at the level expected in leading biotech organizations, this individual will drive end-to-end program execution, establish strong delivery governance, and ensure alignment between scientific, corporate, and technology priorities. This role requires a balance of deep program management discipline, technical fluency, and AI-forward thinking, with a strong focus on execution excellence and executive communication.<br> </p>\n<p><span style=\"font-weight: bold\">Job Responsibilities:</span></p>\n<p> </p>\n<p><span style=\"font-weight: bold\">Program &amp; Project Leadership</span></p>\n<ul>\n<li>Lead end-to-end delivery of complex IT programs across:\n<ul>\n<li><span style=\"font-weight: bold\">R&amp;D systems</span> (Clinical, Discovery, Preclinical)</li>\n<li><span style=\"font-weight: bold\">G&amp;A systems</span> (Finance, HR, Legal, collaboration tools)</li>\n<li><span style=\"font-weight: bold\">AI/ML and infrastructure platforms</span></li>\n</ul>\n</li>\n<li>Drive program planning, execution, and delivery across the full <span style=\"font-weight: bold\">Software Development Lifecycle (SDLC)</span></li>\n<li>Manage multiple concurrent initiatives with clear prioritization, resource alignment, and delivery accountability</li>\n<li>Ensure delivery within <span style=\"font-weight: bold\">scope, timeline, budget, and quality expectations</span><br></li>\n</ul>\n<p><span style=\"font-weight: bold\">Delivery Methodology &amp; Execution Excellence</span></p>\n<ul>\n<li>Apply strong expertise in <span style=\"font-weight: bold\">Agile, Waterfall, and hybrid delivery models</span>, selecting the right approach based on program needs</li>\n<li>Establish structured project plans, milestones, and dependencies across technical and business teams</li>\n<li>Proactively manage risks, issues, and interdependencies with a solutions-oriented mindset</li>\n<li>Drive continuous improvement in delivery frameworks, tools, and operational rigor</li>\n</ul>\n<p><span style=\"font-weight: bold\">Cross-Functional IT &amp; Business Partnership</span></p>\n<ul>\n<li>Work closely with IT functions including <span style=\"font-weight: bold\">Security, Infrastructure, Applications, Data/AI, and Enterprise Systems</span></li>\n<li>Partner with business stakeholders across <span style=\"font-weight: bold\">R&amp;D and G&amp;A</span> to define requirements, align priorities, and drive adoption</li>\n<li>Serve as the connective layer between <span style=\"font-weight: bold\">engineering, architecture, and business teams</span> to ensure cohesive execution</li>\n<li>Coordinate internal teams and external vendors/partners</li>\n</ul>\n<p><span style=\"font-weight: bold\">Executive Reporting &amp; Governance</span></p>\n<ul>\n<li>Own program governance, including <span style=\"font-weight: bold\">steering committees, status reporting, and executive updates</span></li>\n<li>Deliver clear, concise, and data-driven reporting on program health, risks, and outcomes</li>\n<li>Translate complex technical initiatives into <span style=\"font-weight: bold\">business-relevant insights for senior leadership</span></li>\n<li>Drive decision-making through structured communication and escalation management</li>\n</ul>\n<p><span style=\"font-weight: bold\">AI &amp; Digital Enablement</span></p>\n<ul>\n<li>Lead and support initiatives involving <span style=\"font-weight: bold\">AI/ML platforms, data infrastructure, and automation</span></li>\n<li>Demonstrate <span style=\"font-weight: bold\">AI literacy</span>, leveraging modern AI tools to improve productivity and delivery outcomes</li>\n<li>Partner with data and engineering teams to enable scalable, production-ready AI solutions</li>\n</ul>\n<p><span style=\"font-weight: bold\">PMO &amp; Operational Leadership</span></p>\n<ul>\n<li>Contribute to building and scaling <span style=\"font-weight: bold\">IT PMO capabilities</span>, standards, and best practices</li>\n<li>Champion consistency in project execution, documentation, and reporting</li>\n<li>Mentor junior team members and promote a culture of accountability and continuous improvement</li>\n</ul>\n<p> </p>\n<p><span style=\"font-weight: bold\">Qualifications:</span><br></p>\n<p><br></p>\n<p><span style=\"font-weight: bold\">Experience</span></p>\n<ul>\n<li>7+ years of experience in <span style=\"font-weight: bold\">technical project/program management</span>, preferably within <span style=\"font-weight: bold\">biotech, pharma, or regulated environments</span></li>\n<li>Proven success delivering complex, cross-functional IT programs supporting <span style=\"font-weight: bold\">R&amp;D and enterprise functions</span></li>\n<li>Experience working in environments comparable to <span style=\"font-weight: bold\">other biopharma</span></li>\n<li>Strong track record of managing <span style=\"font-weight: bold\">enterprise-scale initiatives and executive stakeholders</span></li>\n</ul>\n<p> </p>\n<p><span style=\"font-weight: bold\">Technical &amp; Delivery Expertise</span></p>\n<ul>\n<li>Strong understanding of:\n<ul>\n<li><span style=\"font-weight: bold\">Software Development Lifecycle (SDLC)</span></li>\n<li><span style=\"font-weight: bold\">Agile, Waterfall, and hybrid delivery models</span></li>\n<li>Cloud infrastructure (AWS/Azure/GCP)</li>\n<li>Data platforms and AI/ML ecosystems</li>\n<li>Enterprise applications (Finance, HR, collaboration tools)</li>\n</ul>\n</li>\n<li>Familiarity with <span style=\"font-weight: bold\">GxP, validation, and compliance requirements</span> is a plus.</li>\n</ul>\n<p><span style=\"font-weight: bold\">Leadership &amp; Communication</span></p>\n<ul>\n<li>Exceptional skills in <span style=\"font-weight: bold\">project management, prioritization, and execution discipline</span></li>\n<li>Strong experience with <span style=\"font-weight: bold\">executive reporting and stakeholder communication</span></li>\n<li>Ability to influence without authority and drive alignment across diverse teams</li>\n<li>High degree of ownership, accountability, and attention to detail</li>\n</ul>\n<p><span style=\"font-weight: bold\">AI &amp; Modern Tooling</span></p>\n<ul>\n<li>Demonstrated <span style=\"font-weight: bold\">AI literacy</span>, including practical use of AI tools to enhance productivity, reporting, or delivery workflows</li>\n<li>Interest in applying emerging technologies to improve IT and business outcomes</li>\n</ul>\n<p><span style=\"font-weight: bold\">Education &amp; Certifications</span></p>\n<ul>\n<li>Bachelor’s degree in Computer Science, Engineering, or related field (Master’s preferred)</li>\n<li>PMP, PgMP, Scrum, or equivalent certification preferred</li>\n</ul>\n<p><span style=\"font-weight: bold\">Success Measures</span></p>\n<ul>\n<li>Consistent delivery of programs on time, within scope, and aligned to business outcomes</li>\n<li>High-quality <span style=\"font-weight: bold\">executive visibility and reporting</span> across IT initiatives</li>\n<li>Strong stakeholder satisfaction across R&amp;D, G&amp;A, and IT leadership</li>\n<li>Improved delivery maturity, standardization, and PMO effectiveness</li>\n<li>Successful enablement and adoption of <span style=\"font-weight: bold\">AI and digital initiatives</span></li>\n</ul>\n<p> </p>\n<p><span style=\"font-weight: bold\">Travel Required:</span></p>\n<p><br></p>\n<p> Occasional travel may be required based on business needs. </p>\n<p> </p>\n<p><span style=\"font-weight: bold\">Structure Therapeutics Inc. is an Equal-Opportunity Employer.</span> </p>\n<p>Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $147,000 - $190,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience. </p>\n<p><br></p>\n<p>At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.  </p>\n<p><br></p>\n<p><span style=\"font-weight: bold\">Notice to Recruiters/Staffing Agencies</span> </p>\n<p>Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees. <br></p>\n<p><br></p>\n<p>We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.</p>\n<p><br></p>\n<p>Structure Therapeutics’ receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees.  <br></p>\n<p><br></p>\n<p><span style=\"font-weight: bold\">Fraud Alert</span> </p>\n<p>To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at <a href=\"https://structuretx.bamboohr.com/careers\" target=\"_blank\" rel=\"noopener noreferrer\">BambooHR</a>. <br></p>\n<p><br></p>\n<p>Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources. </p>",
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