Associate Director, Clinical Data Programmer

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity The Clinical Data Management team at Amylyx Pharmaceuticals is seeking an Associate Director, Clinical Data Programmer. This individual will work collaboratively cross-functionally to provide hands-on data management support, programming support and technical leadership to develop, maintain, validate the clinical database, and run computer programs that access, visualize, and report clinical trial data, in accordance with various clinical plans, ICH guidelines, and applicable regulatory requirements. As an Associate Director of Clinical Data Programming, you will be required to program in the appropriate languages to create both textual and graphic displays that facilitate data cleaning and review. Responsibilities Lead the study-specific design, development, and validation of study clinical data capture systems, ensuring data integrity, CDISC compliance and CRO oversight. Supports leading data management activities (i.e. DMP creation, CRF creation, edit checks creation, database lock), assisting with database setup, conduct and closeout phases. Performs UAT of systems and ensures appropriate plans and documentation are in place. Leads the development of SAS macros, data listings, summary tables and visualizations for supporting periodic and ad hoc data review. Manages external vendor compliance and quality checks. Supports Clinical Operations, Biostatistics and Data Management by providing data insight and solving technical data challenges. Ensures databases adherences to SOPs, 21CRF Part 11, ICH-GCP and CDISC Standards (CDASH/SDTM) Acts as a subject matter expert in leading technical initiatives and data management Required Qualifications Bachelor’s degree or higher in Life Science or related discipline 8+ years of experience in clinical data management Extensive experience with clinical data systems (particularly Medidata Rave) and languages like SAS, R or Python Proven experience in clinical trial programming and database management Knowledge of Clinical Data Standards such as CDISC CDASH, and SDTM Provide strong support to Data Management Experience creating advanced interactive data visualizations from raw data using multi-languages and applications such as Using SAS, R, Python, RShiny, Power BI, Tableau, Spotfire etc. Ability to manage multiple projects simultaneously, to manage conflicting priorities, and to be flexible when priorities change. Excellent written and verbal communication skills and organizational and documentation skills. Work Location and Conditions At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee. You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation. You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communicate via video conference, etc.) at your remote locatio Compensation The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Estimated Pay Range $183,000 — $206,000 USD To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn . To return to our website please click here . Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

{
  "content_hash": "9c167fd6bed6e3713cb0abd33953ae208ca3b264ad39c4bc7768d75e8a3c200f",
  "source_hash": "9f0fdd8f93a31c74f8370b74601bd4eb0c504bd78daf0b8e51e013a18f9f50ff",
  "last_changed_at": "2026-05-29T23:00:00.739Z",
  "active_status": "active"
}

{
  "language": "en",
  "location": {
    "raw": "Cambridge, MA",
    "city": "Cambridge",
    "region": "MA",
    "country": "United States",
    "is_remote": true,
    "confidence": 0.9
  },
  "salary_max": 206000,
  "salary_min": 183000,
  "inferred_at": "2026-06-06T07:34:09.060Z",
  "launch_scope": {
    "reason": "english_us_canada",
    "included": true,
    "language": "en",
    "location": {
      "raw": "Cambridge, MA",
      "city": "Cambridge",
      "region": "MA",
      "country": "United States",
      "is_remote": true,
      "confidence": 0.9
    },
    "countries": [
      "United States"
    ]
  },
  "remote_policy": "remote",
  "salary_period": "year",
  "workplace_type": "remote",
  "salary_currency": "USD"
}

{}

{
  "title": "Associate Director, Clinical Data Programmer",
  "offices": [
    {
      "id": 4009590004,
      "name": "United States",
      "location": "Cambridge, Massachusetts, United States",
      "child_ids": [],
      "parent_id": null
    }
  ],
  "language": "en",
  "location": {
    "name": "Cambridge, MA"
  },
  "metadata": [],
  "updated_at": "2026-04-09T10:09:12-04:00",
  "departments": [
    {
      "id": 4052479004,
      "name": "313 - Biometrics",
      "child_ids": [],
      "parent_id": null
    }
  ],
  "company_name": "Amylyx Pharmaceuticals",
  "requisition_id": 5033124004,
  "first_published": "2026-03-05T17:02:39-05:00",
  "application_deadline": null
}