Senior Product Manager, HCP Marketing

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale. Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges. Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX. Together we are moving psychiatry forward—beyond better, into a boundless future. Join us! Definium Therapeutics is seeking a highly motivated Senior Product Manager, HCP Marketing to support the development and execution of HCP marketing strategy for our lead brand. Reporting to the Senior Director, Marketing this individual will play a key role in shaping and implementing HCP promotional initiatives to support launch readiness and commercial success. The role requires a strategic, hands-on marketer who can translate brand strategy into impactful execution across personal and non-personal promotion, while effectively leading day-to-day collaboration with Definium’s Agency of Record (AOR) and cross-functional internal stakeholders. The ideal candidate brings strong pharmaceutical marketing experience, proven HCP promotional expertise, and the ability to thrive in a fast-paced, entrepreneurial biotech environment. Responsibilities: Support development and execution of HCP marketing strategy aligned with brand objectives and commercial priorities Contribute to brand planning, launch readiness, and tactical planning processes Help shape HCP promotional strategy and messaging based on customer insights, market dynamics, and competitive intelligence Translate complex scientific and clinical data into clear, compelling HCP-focused promotional narratives Identify opportunities to optimize HCP engagement across customer touchpoints and channels Lead development and execution of HCP promotional initiatives to support brand performance and launch objectives establishing scalable commercial processes and operating discipline within a growing organization Own assigned promotional workstreams from strategy through execution, measurement, and optimization ensuring flawless delivery while balancing speed, quality and compliance Develop tactical plans aligned with approved strategic direction, including timelines, budgets, and execution plans Serve as primary day-to-day marketing lead with the AOR across HCP promotional initiatives Provide clear strategic direction, feedback, and decision-making to agency partners to ensure high-quality deliverables Partner closely with Medical, Regulatory, Legal, Commercial Operations, Sales, Market Access, Analytics, and Market Research teams to drive aligned execution Lead promotional materials through review and approval processes in partnership with cross-functional stakeholders Leverage market research, analytics, field insights, and competitive intelligence to inform decision-making Monitor performance of promotional initiatives and identify opportunities for optimization Manage HCP marketing budgets across assigned initiatives tracking timelines, milestones, deliverables, and agency spend Qualifications Minimum bachelor’s degree required; advanced degree (MBA, PharmD, MS, or related field) preferred Minimum 7 years pharmaceutical or biotech commercial experience HCP marketing experience with demonstrated promotional ownership Proven experience developing and executing HCP promotional campaigns Ability to translate scientific complexity into effective commercial promotion Strong strategic thinking with demonstrated executional excellence Strong cross-functional collaboration and stakeholder management capabilities Strong communication and platform skills (will be the face of marketing to the field force) Analytical mindset with ability to draw actionable insights from multiple data sources Experience managing agency partners required Experience working within promotional review / MLR processes required Launch experience strongly preferred CNS / psychiatry / specialty pharmaceutical experience preferred Experience in small biotech or fast-paced growth environments strongly preferred Up to 40% travel will be required based upon business needs The starting base pay range for this position is $170,000.00 - $197,911.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location. Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including: 100% paid health benefits including Medical, Dental and Vision for you and your dependents 401(k) program with company match and vesting after the turn of the first month after your start date Flexible time off Generous parental leave and some fun fringe perks!

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