Senior Director, Clinical Data Management

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior Director of Clinical Data Management provides high-level leadership for data management functions within clinical research, focusing on strategic development, operational execution, and regulatory compliance to ensure data integrity for clinical trials. Key responsibilities include leading and managing data management teams, establishing and enforcing data management policies and procedures, overseeing departmental budgets, collaborating with cross-functional teams and vendors, and ensuring data management processes meet regulatory standards. This role requires extensive experience in clinical data management, strong leadership and communication skills, expertise in clinical trial methodologies, and a deep understanding of regulatory requirements including submissions and data management systems. Required Skills, Experience and Education: Define and implement the overall vision, strategy, and goals for the clinical data management department, including developing and enforcing departmental SOPs. Lead, manage, and develop data management teams, handling resource planning, staff training, and performance reviews. Develop and monitor KPIs for data quality and operational performance. Manage relationships with Contract Research Organizations (CROs) and other data management vendor partners, ensuring they meet quality and performance standards. Forecast, manage, and provide oversight for departmental budgets, including internal and external expenditures. Ensure data integrity, quality, and compliance with regulatory requirements (e.g., FDA, ICH, GCPs) and internal company policies. Experience with global trials and regulatory submissions (FDA, EMA). In-depth understanding of industry standards related to clinical data management (e.g., medical dictionary coding). Guide data management activities for regulatory submissions and represent the department during regulatory inspections and internal audits. Serve as a key liaison and collaborate effectively with cross-functional teams (e.g., Clinical, Quality, Regulatory) and key external stakeholders. Extensive experience in clinical data management and systems, with proven leadership experience in oncology therapeutic area. Proficient knowledge of EDC systems (e.g., Medidata Rave), CDISC standards, and clinical trial processes. Drive innovation and continuous process improvement within data management by implementing new technologies and advanced systems to enhance productivity and efficiency. Demonstrated ability to lead, motivate, and develop teams. Excellent communication and interpersonal skills to effectively collaborate with diverse teams and stakeholders. Strong problem-solving and decision-making abilities to resolve complex issues and drive solutions. MS, BS/BA degree, or other suitable qualification with relevance to the field. 17 or more years’ direct experience in clinical data management in the biotechnology OR Pharmaceutical industry. Preferred Skills: A degree in life science, health informatics, or a related field. Exposure to real-world data (RWD) and decentralized trial models. Automation and digital transformation initiatives to improve data quality and efficiency (e.g., IXRS, AI/ML tools, RBQM platforms). #LI-Hybrid #LI-DN1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact [email protected] . Base Pay Salary Range $244,000 — $305,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.

{
  "content_hash": "47360f23cef3ea44006cb9344f331e88219033139832bd9fbc08d521474b6f3b",
  "source_hash": "4ddcce8bb15d21330dc773fd7ef6d5898bfb56badecbab11eccd2f977c3f22f6",
  "last_changed_at": "2026-06-03T11:13:27.073Z",
  "active_status": "active"
}

{
  "language": "en",
  "location": {
    "raw": "Redwood City, California, United States",
    "city": "Redwood City",
    "region": "CA",
    "country": "United States",
    "is_remote": false,
    "confidence": 0.95
  },
  "salary_max": 305000,
  "salary_min": 244000,
  "inferred_at": "2026-06-04T11:13:54.743Z",
  "launch_scope": {
    "reason": "english_us_canada",
    "included": true,
    "language": "en",
    "location": {
      "raw": "Redwood City, California, United States",
      "city": "Redwood City",
      "region": "CA",
      "country": "United States",
      "is_remote": false,
      "confidence": 0.95
    },
    "countries": [
      "United States"
    ]
  },
  "remote_policy": "hybrid",
  "salary_period": "year",
  "workplace_type": "hybrid",
  "salary_currency": "USD"
}

{}

{
  "title": "Senior Director, Clinical Data Management",
  "offices": [
    {
      "id": 4008124003,
      "name": "Redwood City, CA",
      "location": "Redwood City, California, United States",
      "child_ids": [],
      "parent_id": null
    }
  ],
  "language": "en",
  "location": {
    "name": "Redwood City, California, United States"
  },
  "metadata": [],
  "updated_at": "2026-06-02T11:21:41-04:00",
  "departments": [
    {
      "id": 4161446003,
      "name": "Clinical Data Science, Analytics, & Systems",
      "child_ids": [],
      "parent_id": 4137474003
    }
  ],
  "company_name": "Revolution Medicines",
  "requisition_id": 5725382003,
  "first_published": "2026-04-10T17:56:13-04:00",
  "application_deadline": null
}